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How to get fromFlorence to Mesagneby train (Trenitalia), bus, car, plane, or train

Find Transport to Mesagne

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There are 9 ways to get from Florence to Mesagne by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Firenze S.M.N. to Brindisitrain train Fr
    8h 20m
    €120–199
  2. Bus

    cheapest
    1. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 1518 / ...
    2. Take the bus from Siena Central Train Station to Brindisi Istituto Professionale Falconebus bus Itabus
    14h 2m
    €48–87
  3. Bus via Taranto

    1. Take the bus from Florence Villa Constanza Bus Station to Tarantobus bus 576
    2. Take the bus from Taranto - p.zza Gesù to Mesagnebus bus E18
    13h 30m
    €77–114
  4. Drive  789.3 km

    1. Drive from Florence to Mesagnecar car 789.3 km
    8h 16m
    €128–185
  5. Fly from Florence Peretola Airport

    1. Fly from Florence Peretola Airport (FLR) to Brindisi Airport (BDS)plane plane FLR - BDS
    5h 56m
    €89–234
  6. Train via Rome

    1. Take the train from Firenze Santa Maria Novella to Roma Terminitrain train 8111 / ...
    2. Take the train from Roma Termini to Brindisitrain train Fr / ...
    9h 10m
    €112–193
  7. Train to Bologna Guglielmo Marconi Airport, fly

    1. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    2. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Brindisi Airport (BDS)plane plane BLQ - BDS
    4h 48m
    €57–251
  8. Train to Pisa International Airport, fly

    1. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    2. Fly from Pisa International Airport (PSA) to Brindisi Airport (BDS)plane plane PSA - BDS
    5h 30m
    €71–252
  9. Train to Fiumicino International Airport, fly

    1. Take the train from Firenze S.M.N. to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Brindisi Airport (BDS)plane plane FCO - BDS
    6h 2m
    €63–249

Florence Peretola Airport (FLR) to Brindisi Airport (BDS) flights

Calendar20Weekly Planes
Duration4h 6mAverage Duration
Ticket€49Cheapest Price
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Comparing Your Travel Options

What companies run services between Florence, Italy and Mesagne, Italy?

Trenitalia Frecce operates a train from Firenze S.M.N. to Brindisi twice daily. Tickets cost €110–200 and the journey takes 7h 13m. Alternatively, you can take a bus from Florence Villa Constanza Bus Station to Mesagne via Taranto, Parco Cimino, Taranto Via Cesare Battisti, and Taranto - p.zza Gesù in around 13h 30m.

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