There are 12 ways to get from Florence to Mussomeli by plane, train, ferry, car, car ferry, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Florence Peretola Airport to Palermo Airport, train
best- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
- Take the train from Palermo Aeroporto to Cammarata-S.G.Geminitrain
5h 50m€111–277Fly Florence Peretola Airport to Catania–Fontanarossa Airport, bus
cheapest- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
7h 32m€37–199Train, ferry
- Take the train from Firenze S.M.N. to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Termini Imeresetrain Re
- Take the train from Termini Imerese to Acquaviva-Casteltermtrain Re
13h 22mDrive, car ferry
- Drive from Florence to Civitavecchia Portcar
- Take the carferry from Civitavecchia Port to Palermo Portocarferry
- Drive from Palermo Porto to Mussomelicar
18h 16m€116–167Bus
- Take the bus from Florence Villa Constanza Bus Station to Caltanissettabus N528
- Take the bus from Caltanissetta to Mussomelibus
21h 12m€105–157Train to Pisa International Airport, fly to Palermo Airport, train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
- Take the train from Palermo Aeroporto to Cammarata-S.G.Geminitrain
6h 59m€98–315Train to Bologna Guglielmo Marconi Airport, fly to Palermo Airport, train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Palermo Airport (PMO)plane BLQ - PMO
- Take the train from Palermo Aeroporto to Cammarata-S.G.Geminitrain
6h 27m€73–314Train to Bologna Guglielmo Marconi Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Catania–Fontanarossa Airport (CTA)plane BLQ - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
8h 8m€40–266Train to Pisa International Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Firenze S.M.N. to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
8h 45m€61–237Train (Trenitalia)
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Acquaviva-Casteltermtrain Re
15h 16m€142–269Train #2
- Take the train from Firenze Santa Maria Novella to Roma Terminitrain
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Acquaviva-Casteltermtrain Re
15h 16m€145–258Bus via Canicattì
- Take the bus from Florence Villa Constanza Bus Station to Canicattìbus
- Take the bus from Caltanissetta to Mussomelibus
23h 47m€189–272
Florence Peretola Airport (FLR) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from Florence to Mussomeli is to train and fly and bus which costs €40 - €270 and takes 8h 8m.
The fastest way to get from Florence to Mussomeli is to fly and train which takes 5h 50m and costs €110 - €280.
No, there is no direct bus from Florence station to Mussomeli. However, there are services departing from Florence Villa Constanza Bus Station and arriving at Mussomeli via Caltanissetta. The journey, including transfers, takes approximately 21h 12m.
No, there is no direct train from Florence to Mussomeli. However, there are services departing from Firenze S.M.N. and arriving at Acquaviva-Castelterm via Roma Termini and Termini Imerese. The journey, including transfers, takes approximately 15h 16m.
The distance between Florence and Mussomeli is 786 km.
The best way to get from Florence to Mussomeli without a car is to train and ferry which takes 13h 22m and costs .
It takes approximately 5h 50m to get from Florence to Mussomeli, including transfers.
Florence to Mussomeli bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Mussomeli train services, operated by Trenitalia Frecce, depart from Firenze S.M.N. station.
The best way to get from Florence to Mussomeli is to bus which takes 21h 12m and costs €100 - €160. Alternatively, you can train, which costs €140 - €270 and takes 15h 16m.
What companies run services between Florence, Italy and Mussomeli, Italy?
You can take a bus from Florence Villa Constanza Bus Station to Mussomeli via Caltanissetta and Caltanissetta in around 21h 12m. Alternatively, you can take a train from Firenze S.M.N. to Mussomeli via Roma Termini, Termini Imerese, and Acquaviva-Castelterm in around 15h 16m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–210
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €30–170
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Alghero
- Ave. Duration
- 3h 35m
- When
- Tuesday
- Estimated price
- €30–170
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Bari
- Ave. Duration
- 3h 55m
- When
- Sunday
- Estimated price
- €30–170
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €30–210
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 47m
- When
- Tuesday and Thursday
- Estimated price
- €30–210
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 3h 35m
- When
- Wednesday and Saturday
- Estimated price
- €30–210
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €30–180
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 25m
- When
- Thursday
- Estimated price
- €30–180
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €30–180
- Website
- volotea.com
Flights from Florence Peretola Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €20–140
Flights from Florence Peretola Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €85–180
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- €65–180
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €16–120
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €85–180
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- €85–200
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €85–180
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- €65–180
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €85–180
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- €85–200
- Website
- flyulendo.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €22–75
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €12–120
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €16–90
- Website
- vueling.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €35–200
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Palermo Aeroporto to Cammarata-S.G.Gemini
- Ave. Duration
- 1h 51m
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Website
- Trenitalia
Train from Messina Centrale to Termini Imerese
- Ave. Duration
- 2h 21m
- Frequency
- Hourly
- Estimated price
- €22–30
- Website
- Trenitalia
Train from Termini Imerese to Acquaviva-Castelterm
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Palermo Aeroporto to Cammarata-S.G.Gemini
- Ave. Duration
- 1h 51m
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Palermo Aeroporto to Cammarata-S.G.Gemini
- Ave. Duration
- 1h 51m
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Termini Imerese to Acquaviva-Castelterm
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Termini Imerese to Acquaviva-Castelterm
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Napoli Afragola
- Ave. Duration
- 2h 49m
- Frequency
- Hourly
- Estimated price
- €65–110
- Website
- Trenitalia Frecce
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 4h 4m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 30 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze S.M.N. to Napoli Afragola
- Ave. Duration
- 2h 5m
- Frequency
- 4 times a day
- Estimated price
- €55–90
- Website
- Italo Treno
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 5h 37m
- Frequency
- Once daily
- Estimated price
- €50–80
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 38 min
- Frequency
- 4 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 38 min
- Frequency
- 4 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
Train from Firenze Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- €30–50
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Messina Centrale to Termini Imerese
- Ave. Duration
- 2h 28m
- Frequency
- 4 times a day
- Estimated price
- €19–40
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €27–55
- Website
- Trenitalia Intercity
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 10h 57m
- Frequency
- 4 times a day
- Estimated price
- €85–170
- Website
- Trenitalia Intercity
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 10h 57m
- Frequency
- 4 times a day
- Estimated price
- €85–170
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Caltanissetta
- Ave. Duration
- 18h 50m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Flixbus
- Phone
- +39 0912742800
- [email protected]
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Florence Villa Constanza Bus Station to Canicattì
- Ave. Duration
- 18h 37m
- Frequency
- Twice a week
- Estimated price
- €180–260
- Website
- Onebus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €60–85
- Website
- Grandi Navi Veloci
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Booking & Getting There
Florence to Mussomeli bus services, operated by FlixBus, arrive at Caltanissetta station.
Florence to Mussomeli train services, operated by Trenitalia Frecce, arrive at Roma Termini station.
Book your Florence to Mussomeli train tickets online with Omio.
There are 180+ hotels available in Mussomeli.































