There are 9 ways to get from Florence to Mussomeli by plane, train, ferry, car, car ferry, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Florence Peretola Airport to Palermo Airport, train
best- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
- Take the train from Palermo Centrale to Acquaviva-Casteltermtrain
6h 7m€99–252Fly Florence Peretola Airport to Catania–Fontanarossa Airport, bus
cheapest- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
7h 32m€39–199Train, ferry
- Take the train from Firenze S.M.N. to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Termini Imeresetrain Re
- Take the train from Termini Imerese to Acquaviva-Casteltermtrain Re
13h 18mDrive, car ferry
- Drive from Florence to Civitavecchia Portcar
- Take the carferry from Civitavecchia Port to Palermo Portocarferry
- Drive from Palermo Porto to Mussomelicar
18h 16m€116–166Bus
- Take the bus from Florence Villa Constanza Bus Station to Caltanissettabus N528
- Take the bus from Caltanissetta to Mussomelibus
21h 12m€105–157Train to Pisa International Airport, fly to Palermo Airport, train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
- Take the train from Palermo Centrale to Acquaviva-Casteltermtrain
7h 15m€86–290Train to Bologna Guglielmo Marconi Airport, fly to Palermo Airport, train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Palermo Airport (PMO)plane BLQ - PMO
- Take the train from Palermo Centrale to Acquaviva-Casteltermtrain
6h 43m€60–299Train (Trenitalia)
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Acquaviva-Casteltermtrain Re
15h 16m€142–259Bus via Canicattì
- Take the bus from Florence Villa Constanza Bus Station to Canicattìbus
- Take the bus from Caltanissetta to Mussomelibus
23h 47m€189–272
Florence Peretola Airport (FLR) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from Florence to Mussomeli is to fly and bus which costs €35 - €200 and takes 7h 32m.
The fastest way to get from Florence to Mussomeli is to fly and train which takes 6h 7m and costs €95 - €260.
No, there is no direct bus from Florence station to Mussomeli. However, there are services departing from Florence Villa Constanza Bus Station and arriving at Mussomeli via Caltanissetta. The journey, including transfers, takes approximately 21h 12m.
No, there is no direct train from Florence to Mussomeli. However, there are services departing from Firenze S.M.N. and arriving at Acquaviva-Castelterm via Roma Termini and Termini Imerese. The journey, including transfers, takes approximately 15h 16m.
The distance between Florence and Mussomeli is 794 km.
The best way to get from Florence to Mussomeli without a car is to train and ferry which takes 13h 18m and costs .
It takes approximately 6h 7m to get from Florence to Mussomeli, including transfers.
Florence to Mussomeli bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Mussomeli train services, operated by Trenitalia Frecce, depart from Firenze S.M.N. station.
The best way to get from Florence to Mussomeli is to bus which takes 21h 12m and costs €100 - €160. Alternatively, you can train, which costs €140 - €260 and takes 15h 16m.
What companies run services between Florence, Italy and Mussomeli, Italy?
You can take a bus from Florence Villa Constanza Bus Station to Mussomeli via Caltanissetta and Caltanissetta in around 21h 12m. Alternatively, you can take a train from Firenze S.M.N. to Mussomeli via Roma Termini, Termini Imerese, and Acquaviva-Castelterm in around 15h 16m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–200
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €35–160
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Alghero
- Ave. Duration
- 3h 35m
- When
- Tuesday
- Estimated price
- €35–160
Flights from Bologna Guglielmo Marconi Airport to Palermo Airport via Bari
- Ave. Duration
- 3h 55m
- When
- Sunday
- Estimated price
- €35–160
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Palermo Centrale to Acquaviva-Castelterm
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Messina Centrale to Termini Imerese
- Ave. Duration
- 2h 21m
- Frequency
- Hourly
- Estimated price
- €21–30
- Website
- Trenitalia
Train from Termini Imerese to Acquaviva-Castelterm
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Palermo Centrale to Acquaviva-Castelterm
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Palermo Centrale to Acquaviva-Castelterm
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Termini Imerese to Acquaviva-Castelterm
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- Trenitalia
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Caltanissetta
- Ave. Duration
- 18h 50m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Flixbus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Travelling by boat in Italy
Read the travel guide
Booking & Getting There
Florence to Mussomeli bus services, operated by FlixBus, arrive at Caltanissetta station.
Florence to Mussomeli train services, operated by Trenitalia Frecce, arrive at Roma Termini station.
Book your Florence to Mussomeli train tickets online with Omio.
There are 178+ hotels available in Mussomeli.





