There are 7 ways to get from Florence to Santi Cosma e Damiano by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Minturno-Scauritrain Re
4h 8m€75–143Bus
cheapest- Take the bus from Florence Villa Constanza Bus Station to Cassinobus 532
- Take the bus from CASSINO | Viale Garigliano Via Volturno # f4412 to S. COSMA-DAMIANO | San Lorenzo # f4612bus Fo916d / ...
7h 26m€38–61Drive 401.2 km
- Drive from Florence to Santi Cosma e Damianocar 401.2 km
3h 56m€63–90Fly to Fiumicino International Airport, train, bus
- Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane FLR - FCO
- Take the train from Roma Termini to Formia-Gaetatrain
- Take the bus from FORMIA | Porto # f99992 to COSMA -DAMIANO | staz. Carabineri # f6675bus
6h 3m€80–230Train, bus
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Formia-Gaetatrain Ic
- Take the bus from FORMIA | Porto # f99992 to COSMA -DAMIANO | staz. Carabineri # f6675bus
5h 9m€42–106Train via Formia-Gaeta
- Take the train from Firenze Santa Maria Novella to Roma Terminitrain 8111 / ...
- Take the train from Roma Termini to Formia-Gaetatrain Ic
5h 24m€48–96Fly to Naples Airport, train
- Fly from Florence Peretola Airport (FLR) to Naples Airport (NAP)plane FLR - NAP
- Take the train from Napoli Centrale to Formia-Gaetatrain
7h 38m€102–229
Florence to Santi Cosma e Damiano by bus and foot
Questions & Answers
The cheapest way to get from Florence to Santi Cosma e Damiano is to bus which costs €35 - €65 and takes 7h 26m.
The fastest way to get from Florence to Santi Cosma e Damiano is to drive which takes 3h 56m and costs €60 - €90.
No, there is no direct bus from Florence station to Santi Cosma e Damiano. However, there are services departing from Florence Villa Constanza Bus Station and arriving at S. COSMA-DAMIANO | San Lorenzo # f4612 via CASSINO | Viale Garigliano Via Volturno # f4412. The journey, including transfers, takes approximately 7h 26m.
No, there is no direct train from Florence to Santi Cosma e Damiano. However, there are services departing from Firenze S.M.N. and arriving at Minturno-Scauri via Roma Termini. The journey, including transfers, takes approximately 4h 8m.
The distance between Florence and Santi Cosma e Damiano is 411 km. The road distance is 401.2 km.
The best way to get from Florence to Santi Cosma e Damiano without a car is to train which takes 4h 8m and costs €75 - €150.
It takes approximately 4h 8m to get from Florence to Santi Cosma e Damiano, including transfers.
Florence to Santi Cosma e Damiano bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Santi Cosma e Damiano train services, operated by Trenitalia Frecce, depart from Firenze S.M.N. station.
The best way to get from Florence to Santi Cosma e Damiano is to train which takes 4h 8m and costs €75 - €150. Alternatively, you can bus, which costs €35 - €65 and takes 7h 26m.
What companies run services between Florence, Italy and Santi Cosma e Damiano, Lazio, Italy?
You can take a train from Firenze S.M.N. to Santi Cosma e Damiano via Roma Termini and Minturno-Scauri in around 4h 8m. Alternatively, you can take a bus from Florence Villa Constanza Bus Station to S. COSMA-DAMIANO | San Lorenzo # f4612 via Cassino and CASSINO | Viale Garigliano Via Volturno # f4412 in around 7h 26m.
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Fiumicino International Airport
- Ave. Duration
- 53 min
- When
- Every day
- Estimated price
- €60–160
Flights from Florence Peretola Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- €130–190
- Website
- easyjet.com
Flights from Florence Peretola Airport to Naples Airport via Olbia
- Ave. Duration
- 3h 5m
- When
- Tuesday
- Estimated price
- €110–260
Flights from Florence Peretola Airport to Naples Airport via Palermo
- Ave. Duration
- 4h 5m
- When
- Monday
- Estimated price
- €70–230
- Website
- ryanair.com
Flights from Florence Peretola Airport to Naples Airport via Catania
- Ave. Duration
- 4h
- When
- Monday, Friday, and Sunday
- Estimated price
- €90–200
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 52m
- Frequency
- Every 15 minutes
- Estimated price
- €35–80
- Schedules at
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 52m
- Frequency
- Every 15 minutes
- Estimated price
- €35–80
- Schedules at
- Trenitalia Frecce
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- Trenitalia
Train from Roma Termini to Minturno-Scauri
- Ave. Duration
- 1h 46m
- Frequency
- Every 30 minutes
- Estimated price
- €17–28
- Website
- Trenitalia
Train from Roma Termini to Formia-Gaeta
- Ave. Duration
- 1h 34m
- Frequency
- Every 30 minutes
- Estimated price
- €16–26
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- Trenitalia
Train from Roma Termini to Formia-Gaeta
- Ave. Duration
- 1h 34m
- Frequency
- Every 30 minutes
- Estimated price
- €16–26
- Website
- Trenitalia
Train from Roma Termini to Formia-Gaeta
- Ave. Duration
- 1h 34m
- Frequency
- Every 30 minutes
- Estimated price
- €16–26
- Website
- Trenitalia
Train from Napoli Centrale to Formia-Gaeta
- Ave. Duration
- 1h 16m
- Frequency
- Every 30 minutes
- Estimated price
- €10–18
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €28–60
- Website
- Trenitalia Intercity
Train from Roma Termini to Formia-Gaeta
- Ave. Duration
- 1h 7m
- Frequency
- Hourly
- Estimated price
- €13–28
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €28–60
- Website
- Trenitalia Intercity
Train from Roma Termini to Formia-Gaeta
- Ave. Duration
- 1h 7m
- Frequency
- Hourly
- Estimated price
- €13–28
- Website
- Trenitalia Intercity
Train from Roma Termini to Formia-Gaeta
- Ave. Duration
- 1h 7m
- Frequency
- Hourly
- Estimated price
- €13–28
- Website
- Trenitalia Intercity
Train from Napoli Centrale to Formia-Gaeta
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €9–19
- Website
- Trenitalia Intercity
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze Santa Maria Novella to Roma Termini
- Ave. Duration
- 2h 7m
- Frequency
- Every 30 minutes
- Estimated price
- €30–65
- Website
- Italo Treno
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Cassino
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- €35–60
- Website
- Flixbus
- Phone
- 800 174 471
- Website
- Cotral S.p.A.
Bus from CASSINO | Viale Garigliano Via Volturno # f4412 to S. COSMA-DAMIANO | San Lorenzo # f4612
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- €3–4
- Schedules at
- Cotral S.p.A.
Bus from FORMIA | Porto # f99992 to COSMA -DAMIANO | staz. Carabineri # f6675
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €1–3
- Schedules at
- Cotral S.p.A.
Bus from FORMIA | Porto # f99992 to COSMA -DAMIANO | staz. Carabineri # f6675
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €1–3
- Schedules at
- Cotral S.p.A.
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More Questions & Answers
Florence to Santi Cosma e Damiano bus services, operated by FlixBus, arrive at Cassino station.
Florence to Santi Cosma e Damiano train services, operated by Trenitalia Frecce, arrive at Roma Termini station.
Yes, the driving distance between Florence to Santi Cosma e Damiano is 401 km. It takes approximately 3h 56m to drive from Florence to Santi Cosma e Damiano.
Book your Florence to Santi Cosma e Damiano train tickets online with Omio.
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