There are 7 ways to get from Florence to Sistine Chapel by train, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, line 64 bus
best- Take the train from Florence Santa Maria Novella to Roma Terminitrain 9927 / ...
- Take the bus from Termini to Cavalleggeri/S. Pietrobus 64 / ...
1h 52m€34–74Bus
cheapest- Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...
4h 21m€18–52Drive 275.9 km
- Drive from Florence to Sistine Chapelcar 275.9 km
2h 42m€44–63Fly from Florence Peretola Airport
- Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane FLR - FCO
3h 8m€65–198Train via Termini (Trenitalia)
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
2h 35m€29–84Train
- Take the train from Firenze Santa Maria Novella to Roma Tiburtinatrain 8902 / ...
2h 41m€34–67Train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Fiumicino International Airport (FCO)plane BLQ - FCO
3h 51m€53–205
Florence to Sistine Chapel by bus and foot
Questions & Answers
The cheapest way to get from Florence to Sistine Chapel is to bus which costs €18 - €55 and takes 4h 21m.
The fastest way to get from Florence to Sistine Chapel is to train and line 64 bus which takes 1h 52m and costs €30 - €75.
No, there is no direct bus from Florence station to Sistine Chapel. However, there are services departing from Florence Villa Constanza Bus Station and arriving at Cavalleggeri/S. Pietro via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 21m.
No, there is no direct train from Florence to Sistine Chapel. However, there are services departing from Firenze S.M.N. and arriving at Roma Termini via . The journey, including transfers, takes approximately 2h 35m.
The distance between Florence and Sistine Chapel is 267 km. The road distance is 275.9 km.
The best way to get from Florence to Sistine Chapel without a car is to train and line 64 bus which takes 1h 52m and costs €30 - €75.
It takes approximately 1h 52m to get from Florence to Sistine Chapel, including transfers.
Florence to Sistine Chapel bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Sistine Chapel train services, operated by Trenitalia Frecce, depart from Firenze S.M.N. station.
The best way to get from Florence to Sistine Chapel is to bus which takes 4h 21m and costs €18 - €55. Alternatively, you can fly, which costs €60 - €200 and takes 3h 8m, you could also train via Termini, which costs €29 - €85 and takes 2h 35m.
What companies run services between Florence, Italy and Sistine Chapel, Vatican City?
FlixBus operates a bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina hourly. Tickets cost €24–40 and the journey takes 3h 15m. Three other operators also service this route. Alternatively, ITA Airways flies from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO) 4 times a day.
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Fiumicino International Airport
- Ave. Duration
- 53 min
- When
- Every day
- Estimated price
- €60–150
Flights from Bologna Guglielmo Marconi Airport to Fiumicino International Airport
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- €55–110
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 9m
- Frequency
- 4 times a day
- Estimated price
- €30–65
- Website
- https://www.italotreno.it/en
Train from Firenze Santa Maria Novella to Roma Tiburtina
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €30–65
- Website
- https://www.italotreno.it/en
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 45 min
- Frequency
- 4 times a day
- Estimated price
- €11–23
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 52m
- Frequency
- Every 15 minutes
- Estimated price
- €35–80
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 38 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–27
- Schedules at
- trenitalia.com
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 4h 6m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €28–60
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- 3 times a day
- Estimated price
- €9–20
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- [email protected]
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 06 46951
- Website
- atac.roma.it
Bus from Termini to Cavalleggeri/S. Pietro
- Ave. Duration
- 28 min
- Frequency
- Every 10 minutes
- Estimated price
- €2–9
- Website
- https://www.atac.roma.it/en
- 100-minute intergrated ticket
- €2
- 24-hour ticket
- €9
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- €24–40
- Website
- https://www.flixbus.co.uk
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- €24–45
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- €17–35
- Website
- https://www.itabus.it/en/home
- Phone
- +39 0972 24590
- [email protected]
- Website
- autolineemoretti.it
Bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a week
- Estimated price
- €19–22
- Schedules at
- autolineemoretti.it
Want to know more about travelling around Vatican City
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More Questions & Answers
Florence to Sistine Chapel bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Florence to Sistine Chapel train services, operated by Trenitalia Frecce, arrive at Roma Termini station.
Yes, the driving distance between Florence to Sistine Chapel is 276 km. It takes approximately 2h 42m to drive from Florence to Sistine Chapel.
There are 21714+ hotels available in Sistine Chapel.