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How to get fromFlorence to Chicagoby plane, bus (Flixbus), bus, train, or car

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There are 8 ways to get from Florence to Chicago by plane, bus (Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Covington to Chicago Midway International Airport

    best
    1. Fly from Covington (CVG) to Chicago Midway International Airport (MDW)plane plane CVG - MDW
    3h 17m
    $154–366

  2. Bus via New Paris

    cheapest
    1. Take the bus from Greyhound Station Cincinnati to Richmond Bsb, INbus bus Cincinnati
    2. Take the bus from Richmond, IN to Chicagobus bus Columbus-Chicago
    11h 54m
    $34–142

  3. Bus (Flixbus)

    1. Take the bus from Cincinnati to Chicago Bus Stationbus bus FlixBus 2514 / ...
    8h 30m
    $48–88

  4. Bus, train

    1. Take the bus from Cincinnati to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus bus
    3. Take the train from Indianapolis to Chicago Union Stationtrain train
    10h
    $120–222

  5. Drive 289.4 mi

    1. Drive from Florence to Chicagocar car 289.4 mi
    5h 15m
    $53–77

  6. Fly Covington to Chicago O'Hare International Airport

    1. Fly from Covington (CVG) to Chicago O'Hare International Airport (ORD)plane plane CVG - ORD
    3h 45m
    $154–856

  7. Drive to Louisville International Airport, fly to Chicago Midway International Airport

    1. Drive from Florence to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW)plane plane SDF - MDW
    3h 25m
    $69–379

  8. Drive to Blue Grass Airport, fly to Chicago O'Hare International Airport

    1. Drive from Florence to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Chicago O'Hare International Airport (ORD)plane plane LEX - ORD
    3h 47m
    $75–414

Florence to Chicago by bus (Flixbus)

Calendar10Weekly Buses
Duration8h 30mAverage Duration
Ticket$48Cheapest Price
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Questions & Answers

Map of how to get from Florence to Chicago.ExpandLaunch map view
  • Distance: 268.4 mi
  • Duration: 3h 17m

What companies run services between Florence, KY, USA and Chicago, IL, USA?

Southwest Airlines flies from Covington (CVG) to Chicago Midway International Airport (MDW) twice daily. Alternatively, Flixbus USA operates a bus from Cincinnati to Chicago Bus Station once daily. Tickets cost $45–80 and the journey takes 6h.

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