There are 6 ways to get from Florence to Amarillo by plane, bus (Greyhound, Flixbus), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Florence Regional Airport
best- Fly from Florence Regional Airport (FLO) to Rick Husband Amarillo International Airport (AMA)plane FLO - AMA
8h 13m$143–590Bus via St. Louis
- Take the bus from Florence Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Amarillo Multimodal Transfer Stabus
35h 20m$286–462Drive 1,390.1 mi
- Drive from Florence to Amarillocar 1,390.1 mi
22h 10m$246–355Bus to Myrtle Beach, fly
- Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus
- Fly from Myrtle Beach (MYR) to Rick Husband Amarillo International Airport (AMA)plane MYR - AMA
9h 2m$147–520Bus
- Take the bus from Florence Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Amarillo Multimodal Transfer Stabus
35h 25m$281–442Bus #2
- Take the bus from Florence Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Fort Worth Downtownbus
- Take the bus from Fort Worth Downtown to Amarillo Multimodal Transfer Stabus
35h 35m$275–420
Florence to Amarillo by bus
Comparing Your Travel Options
The cheapest way to get from Florence to Amarillo is to drive which costs $240 - $360 and takes 22h 10m.
The fastest way to get from Florence to Amarillo is to fly which takes 8h 13m and costs $140 - $600.
No, there is no direct bus from Florence station to Amarillo. However, there are services departing from Florence Bus Station and arriving at Amarillo Multimodal Transfer Sta via Atlanta Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 35h 20m.
The distance between Florence and Amarillo is 1267 miles. The road distance is 1398.2 miles.
The best way to get from Florence to Amarillo without a car is to bus via St. Louis which takes 35h 20m and costs $280 - $470.
It takes approximately 8h 13m to get from Florence to Amarillo, including transfers.
Florence to Amarillo bus services, operated by Greyhound USA, depart from Florence Bus Station.
The best way to get from Florence to Amarillo is to fly which takes 8h 13m and costs $140 - $600. Alternatively, you can bus via St. Louis, which costs $280 - $470 and takes 35h 20m.
Florence to Amarillo bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Amarillo is 1h behind Florence. It is currently 12:12 AM in Florence and 11:12 PM in Amarillo.
What companies run services between Florence, SC, USA and Amarillo, TX, USA?
American Airlines and Southwest Airlines fly from Florence Regional Airport (FLO) to Rick Husband Amarillo International Airport (AMA) twice daily. Alternatively, you can take a bus from Florence Bus Station to Amarillo Multimodal Transfer Sta via Atlanta Bus Station and St Louis Bus Station in around 35h 20m.
- Website
- aa.com
Flights from Florence Regional Airport to Rick Husband Amarillo International Airport via Charlotte, Dallas/Ft.Worth
- Ave. Duration
- 8h 4m
- When
- Every day
- Estimated price
- $110–550
Flights from Myrtle Beach to Rick Husband Amarillo International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 4m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–460
- Website
- southwest.com
Flights from Florence Regional Airport to Rick Husband Amarillo International Airport via Charlotte, Austin
- Ave. Duration
- 8h 56m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–550
Flights from Myrtle Beach to Rick Husband Amarillo International Airport via Dallas
- Ave. Duration
- 6h
- When
- Saturday
- Estimated price
- $100–460
Flights from Myrtle Beach to Rick Husband Amarillo International Airport via Nashville, Dallas
- Ave. Duration
- 10h 20m
- When
- Saturday
- Estimated price
- $100–470
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $55–85
- Website
- Greyhound
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $100–160
- Website
- Greyhound
Bus from St Louis Bus Station to Amarillo Multimodal Transfer Sta
- Ave. Duration
- 15h
- Frequency
- Twice daily
- Estimated price
- $140–220
- Website
- Greyhound
Bus from Florence Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $55–85
- Website
- Greyhound
Bus from Atlanta Bus Station to Dallas Bus Station
- Ave. Duration
- 17h 55m
- Frequency
- 3 times a day
- Estimated price
- $150–230
- Website
- Greyhound
Bus from Dallas Bus Station to Amarillo Multimodal Transfer Sta
- Ave. Duration
- 8h 50m
- Frequency
- Once daily
- Estimated price
- $85–130
- Website
- Greyhound
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $55–85
- Website
- Greyhound
Bus from Atlanta Bus Station to Dallas Bus Station
- Ave. Duration
- 17h 55m
- Frequency
- 3 times a day
- Estimated price
- $150–230
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 10h 21m
- Frequency
- 5 times a week
- Estimated price
- $90–140
- Schedules at
- Flixbus USA
Bus from Dallas Bus Station to Amarillo Multimodal Transfer Sta
- Ave. Duration
- 8h 10m
- Frequency
- 6 times a week
- Estimated price
- $75–120
- Schedules at
- Flixbus USA
Bus from Dallas Bus Station to Fort Worth Downtown
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $4–8
- Schedules at
- Flixbus USA
Bus from Fort Worth Downtown to Amarillo Multimodal Transfer Sta
- Ave. Duration
- 7h 20m
- Frequency
- 6 times a week
- Estimated price
- $65–100
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Florence to Amarillo is 1398 miles. It takes approximately 22h 10m to drive from Florence to Amarillo.
Book your Florence to Amarillo bus tickets online with Omio and FlixBus.
There are 189+ hotels available in Amarillo.



