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How to get fromFlorence to Baltimoreby train (Amtrak), train, bus, car, plane, or bus (Greyhound, Flixbus)

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There are 10 ways to get from Florence to Baltimore by train (Amtrak), train, bus, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Florence Station to Baltimore Penn Stationtrain train Palmetto / ...
    9h 42m
    $110–260

  2. Bus

    cheapest
    1. Take the bus from Florence Bus Station to Raleigh Bus Stationbus bus Greyhound US0642S / ...
    2. Take the bus from Raleigh Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0670
    10h 25m
    $69–112

  3. Train, bus

    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train Palmetto / ...
    2. Take the bus from Fayetteville Bus Station to Baltimore Downtown Bus Stationbus bus FlixBus N2471 / ...
    10h 6m
    $77–133

  4. Drive  436.3 mi

    1. Drive from Florence to Baltimorecar car 436.3 mi
    7h 37m
    $80–115

  5. Train to Charleston International Airport, fly to Baltimore-Washington International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Baltimore-Washington International Airport (BWI)plane plane CHS - BWI
    6h 38m
    $451–1,161

  6. Bus, bus to Charlotte Douglas International Airport, fly to Baltimore-Washington International Airport

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Baltimore-Washington International Airport (BWI)plane plane CLT - BWI
    7h 50m
    $120–327

  7. Train, bus to Myrtle Beach, fly to Baltimore-Washington International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Baltimore-Washington International Airport (BWI)plane plane MYR - BWI
    8h 2m
    $353–746

  8. Train, train to Raleigh-Durham International Airport, fly to Baltimore-Washington International Airport

    1. Take the train from Florence Station to Selma Stationtrain train
    2. Take the train from Selma Station to Raleigh Union Stationtrain train
    3. Fly from Raleigh-Durham International Airport (RDU) to Baltimore-Washington International Airport (BWI)plane plane RDU - BWI
    8h 28m
    $227–448

  9. Bus, bus to Columbia, fly to Ronald Reagan Washington National Airport, train

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Columbia, SCbus bus
    3. Fly from Columbia (CAE) to Ronald Reagan Washington National Airport (DCA)plane plane CAE - DCA
    4. Take the train from Washington Union Station to Baltimore Penn Stationtrain train
    9h 1m
    $126–1,213

  10. Train, bus to Myrtle Beach, fly to Ronald Reagan Washington National Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Ronald Reagan Washington National Airport (DCA)plane plane MYR - DCA
    4. Take the train from Washington Union Station to Baltimore Penn Stationtrain train
    8h 58m
    $127–1,161

Florence to Baltimore by train (Amtrak)

Calendar14Weekly Trains
Duration9h 42mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

Map of how to get from Florence to Baltimore.ExpandLaunch map view
  • Distance: 447.5 mi
  • Duration: 9h 42m

What companies run services between Florence, SC, USA and Baltimore, MD, USA?

Amtrak operates a train from Florence Station to Baltimore Penn Station twice daily. Tickets cost $110–260 and the journey takes 9h 42m. Alternatively, you can take a bus from Florence Bus Station to Baltimore Downtown Bus Station via Raleigh Bus Station in around 10h 25m.

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