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How to get fromFlorence to Baltimoreby bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

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There are 8 ways to get from Florence to Baltimore by bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Myrtle Beach, fly to Baltimore-Washington International Airport

    best
    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to Baltimore-Washington International Airport (BWI)plane plane MYR - BWI
    5h 6m
    $293–719

  2. Bus

    cheapest
    1. Take the bus from Florence Bus Station to Raleigh Bus Stationbus bus Greyhound US0642 / ...
    2. Take the bus from Raleigh Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0670 / ...
    9h 44m
    $69–135

  3. Train (Amtrak)

    1. Take the train from Florence Station to Baltimore Penn Stationtrain train Palmetto / ...
    9h 42m
    $140–300

  4. Drive 436.3 mi

    1. Drive from Florence to Baltimorecar car 436.3 mi
    7h 37m
    $80–115

  5. Bus to Myrtle Beach, fly to Ronald Reagan Washington National Airport, train

    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to Ronald Reagan Washington National Airport (DCA)plane plane MYR - DCA
    3. Take the train from Washington Union Station to Baltimore Penn Stationtrain train
    6h 2m
    $127–1,104

  6. Train to Charleston International Airport, fly to Baltimore-Washington International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Baltimore-Washington International Airport (BWI)plane plane CHS - BWI
    6h 43m
    $417–1,268

  7. Bus, bus to Charlotte Douglas International Airport, fly to Baltimore-Washington International Airport

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Baltimore-Washington International Airport (BWI)plane plane CLT - BWI
    7h 42m
    $151–414

  8. Train, bus

    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train Palmetto / ...
    2. Take the bus from Fayetteville Bus Station to Baltimore Downtown Bus Stationbus bus FlixBus N2471 / ...
    10h 1m
    $82–154

Florence to Baltimore by train (Amtrak)

Calendar14Weekly Trains
Duration9h 42mAverage Duration
Ticket$140Cheapest Price
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Questions & Answers

Map of how to get from Florence to Baltimore.ExpandLaunch map view
  • Distance: 487.5 mi
  • Duration: 5h 6m

What companies run services between Florence, SC, USA and Baltimore, MD, USA?

Amtrak operates a train from Florence Station to Baltimore Penn Station twice daily. Tickets cost $140–300 and the journey takes 9h 42m. Alternatively, you can take a bus from Florence Bus Station to Baltimore Downtown Bus Station via Raleigh Bus Station in around 9h 44m.

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