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How to get fromFlorence to Bostonby bus, plane, train (Amtrak), bus (Flixbus), car, train, or bus (Greyhound)

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There are 8 ways to get from Florence to Boston by bus, plane, train (Amtrak), bus (Flixbus), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Myrtle Beach, fly to Boston Logan Airport

    best
    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to Boston Logan Airport (BOS)plane plane MYR - BOS
    5h 4m
    $116–407

  2. Train (Amtrak)

    1. Take the train from Florence Station to Ny Moynihan Train Hall At Penn Stationtrain train Palmetto / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train Acela
    16h 57m
    $281–574

  3. Bus

    1. Take the bus from Florence, SC to New York, NYbus bus Florence
    2. Take the bus from NYC Downtown to Bostonbus bus FlixBus 2611
    18h
    $144–201

  4. Drive 829.7 mi

    1. Drive from Florence to Bostoncar car 829.7 mi
    14h 55m
    $152–219

  5. Train to Charleston International Airport, fly to Boston Logan Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Boston Logan Airport (BOS)plane plane CHS - BOS
    6h 46m
    $635–1,016

  6. Bus to Myrtle Beach, fly to Theodore Francis Green State Airport, train

    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to Theodore Francis Green State Airport (PVD)plane plane MYR - PVD
    3. Take the train from TF Green Airport to South Stationtrain train
    7h 32m
    $210–423

  7. Bus, bus to Charlotte Douglas International Airport, fly to Boston Logan Airport

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Boston Logan Airport (BOS)plane plane CLT - BOS
    7h 46m
    $189–362

  8. Bus via Raleigh

    1. Take the bus from Florence Bus Station to Raleigh Bus Stationbus bus
    2. Take the bus from Raleigh Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Bostonbus bus
    19h 5m
    $200–296

Florence to Boston by train (Amtrak)

Calendar14Weekly Trains
Duration16h 57mAverage Duration
Ticket$281Cheapest Price
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Questions & Answers

Map of how to get from Florence to Boston.ExpandLaunch map view
  • Distance: 816.1 mi
  • Duration: 5h 4m

What companies run services between Florence, SC, USA and Boston, MA, USA?

You can take a train from Florence Station to Boston via Ny Moynihan Train Hall At Penn Station in around 16h 57m. Alternatively, you can take a bus from Florence, SC to Boston via New York, NY and NYC Downtown in around 18h.

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