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How to get fromFlorence to Champaignby bus, plane, bus (Greyhound), train (Amtrak), or car

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There are 7 ways to get from Florence to Champaign by bus, plane, bus (Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Myrtle Beach, fly to University Of Illinois Willard Airport

    best
    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to University Of Illinois Willard Airport (CMI)plane plane MYR - CMI
    8h 22m

  2. Fly Florence Regional Airport to Indianapolis, bus

    cheapest
    1. Fly from Florence Regional Airport (FLO) to Indianapolis (IND)plane plane FLO - IND
    2. Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus bus
    8h 30m
    $129–560

  3. Bus

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S / ...
    2. Take the bus from Atlanta Bus Station to Champaign Intermodal Trans Ctrbus bus FlixBus N2521
    22h 20m

  4. Train (Amtrak)

    1. Take the train from Florence Station to Selma Stationtrain train
    2. Take the train from Selma Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Champaign-Urbanatrain train
    32h 54m
    $442–890

  5. Drive 784.6 mi

    1. Drive from Florence to Champaigncar car 784.6 mi
    14h 12m
    $144–207

  6. Bus to Myrtle Beach, fly to Chicago Midway International Airport, bus

    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW)plane plane MYR - MDW
    3. Take the bus from Chicago Midway Airport to Illinois Terminalbus bus
    8h 18m

  7. Bus via Columbus

    1. Take the bus from Florence to Charlottebus bus
    2. Take the bus from Charlotte to Columbusbus bus
    3. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Richmond, INbus bus
    4. Take the bus from Richmond Bsb, IN to Indianapolis, INbus bus
    5. Take the bus from Indianapolis to Champaignbus bus
    24h 40m

Myrtle Beach (MYR) to University Of Illinois Willard Airport (CMI) flights

Calendar27Weekly Planes
Duration6h 39mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Florence to Champaign.ExpandLaunch map view
  • Distance: 761.9 mi
  • Duration: 8h 22m

What companies run services between Florence, SC, USA and Champaign, IL, USA?

You can take a bus from Florence Bus Station to Champaign Intermodal Trans Ctr via Atlanta Bus Station in around 22h 20m. Alternatively, you can take a train from Florence Station to Champaign-Urbana via Selma Station, Raleigh Union Station, and Chicago Union Station in around 32h 54m.

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