There are 7 ways to get from Florence to Champaign by bus, plane, train, train (Amtrak), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Myrtle Beach, fly to University Of Illinois Willard Airport
best- Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus
- Fly from Myrtle Beach (MYR) to University Of Illinois Willard Airport (CMI)plane MYR - CMI
8h 41m$116–455Bus, train
- Take the bus from Florence Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus
- Take the train from Carbondale to Champaign-Urbanatrain
19h 51m$219–349Train (Amtrak)
- Take the train from Florence Station to Selma Stationtrain
- Take the train from Selma Station to Raleigh Union Stationtrain
- Take the train from Raleigh Union Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Champaign-Urbanatrain
32h 54m$707–1,196Drive 784.6 mi
- Drive from Florence to Champaigncar 784.6 mi
14h 12m$130–188Fly Florence Regional Airport to Indianapolis, bus
- Fly from Florence Regional Airport (FLO) to Indianapolis (IND)plane FLO - IND
- Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus
8h 45m$131–611Bus to Myrtle Beach, fly to Chicago O'Hare International Airport, train
- Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus
- Fly from Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD)plane MYR - ORD
- Take the train from Chicago Union Station to Champaign-Urbanatrain
9h 59m$153–440Bus (Greyhound)
- Take the bus from Florence Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus
22h 35m$170–264
Florence to Champaign by bus and train
Comparing Your Travel Options
The cheapest way to get from Florence to Champaign is to drive which costs $130 - $190 and takes 14h 12m.
The fastest way to get from Florence to Champaign is to bus and fly which takes 8h 41m and costs $110 - $460.
No, there is no direct bus from Florence station to Champaign. However, there are services departing from Florence Bus Station and arriving at Champaign Intermodal Trans Ctr via Atlanta Bus Station and Indianapolis Union Station. The journey, including transfers, takes approximately 22h 35m.
No, there is no direct train from Florence station to Champaign. However, there are services departing from Florence Station and arriving at Champaign-Urbana via Selma Station, Raleigh Union Station and Chicago Union Station. The journey, including transfers, takes approximately 32h 54m.
The distance between Florence and Champaign is 758 miles. The road distance is 789.1 miles.
The best way to get from Florence to Champaign without a car is to bus and train which takes 19h 51m and costs $210 - $350.
It takes approximately 8h 41m to get from Florence to Champaign, including transfers.
Florence to Champaign bus services, operated by Greyhound USA, depart from Florence Bus Station.
Florence to Champaign train services, operated by Amtrak, depart from Florence Station.
The best way to get from Florence to Champaign is to train which takes 32h 54m and costs $700 - $1,200. Alternatively, you can bus, which costs $170 - $270 and takes 22h 35m.
What companies run services between Florence, SC, USA and Champaign, IL, USA?
You can take a train from Florence Station to Champaign-Urbana via Selma Station, Raleigh Union Station, and Chicago Union Station in around 32h 54m. Alternatively, you can take a bus from Florence Bus Station to Champaign Intermodal Trans Ctr via Atlanta Bus Station and Indianapolis Union Station in around 22h 35m.
- Website
- aa.com
Flights from Myrtle Beach to University Of Illinois Willard Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 48m
- When
- Every day
- Estimated price
- $75–400
Flights from Myrtle Beach to University Of Illinois Willard Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 50m
- When
- Every day
- Estimated price
- $120–550
Flights from Myrtle Beach to University Of Illinois Willard Airport via Charlotte, Chicago O'Hare International Airport
- Ave. Duration
- 7h 23m
- When
- Every day
- Estimated price
- $75–400
Flights from Florence Regional Airport to Indianapolis via Charlotte
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $90–550
Flights from Myrtle Beach to Chicago O'Hare International Airport
- Ave. Duration
- 2h 41m
- When
- Every day
- Estimated price
- $55–290
Flights from Myrtle Beach to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $55–290
- Website
- united.com
Flights from Myrtle Beach to Chicago O'Hare International Airport
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- $55–290
- Website
- delta.com
Flights from Myrtle Beach to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $60–310
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Carbondale to Champaign-Urbana
- Ave. Duration
- 2h 50m
- Frequency
- 3 times a day
- Estimated price
- $95–160
- Website
- Amtrak
Train from Florence Station to Selma Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $70–120
- Website
- Amtrak
Train from Selma Station to Raleigh Union Station
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $15–25
- Website
- Amtrak
Train from Raleigh Union Station to Chicago Union Station
- Ave. Duration
- 24h 28m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
Train from Chicago Union Station to Champaign-Urbana
- Ave. Duration
- 2h 31m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Website
- Amtrak
Train from Chicago Union Station to Champaign-Urbana
- Ave. Duration
- 2h 31m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Florence Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $12–18
- Website
- Greyhound
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Indianapolis Union Station to Champaign Intermodal Trans Ctr
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Greyhound
Bus from Florence Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $12–18
- Website
- Greyhound
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Atlanta Bus Station to Indianapolis Union Station
- Ave. Duration
- 11h 50m
- Frequency
- 4 times a day
- Estimated price
- $95–150
- Website
- Greyhound
Bus from Indianapolis Union Station to Champaign Intermodal Trans Ctr
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Atlanta Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 8h 21m
- Frequency
- 5 times a week
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Florence to Champaign bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Champaign is 1h behind Florence. It is currently 9:34 PM in Florence and 8:34 PM in Champaign.
Florence to Champaign train services, operated by Amtrak, arrive at Selma Station.
Yes, the driving distance between Florence to Champaign is 789 miles. It takes approximately 14h 12m to drive from Florence to Champaign.
Book your Florence to Champaign train tickets online with Omio.
Book your Florence to Champaign bus tickets online with Omio and FlixBus.
There are 59+ hotels available in Champaign.












