There are 5 ways to get from Florence to Charleston by plane, bus (Greyhound), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Florence Regional Airport (FLO) to Yeager Airport (CRW)plane FLO - CRW
5h$82–417Bus
cheapest- Take the bus from Florence Bus Station to Camdenbus
- Take the bus from Camden to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Charleston, WVbus
10h 15m$58–122Train (Amtrak)
- Take the train from Florence Station to Alexandriatrain Palmetto / ...
- Take the train from Alexandria to Charleston Stationtrain Cardinal
17h 47m$233–510Drive 365.2 mi
- Drive from Florence to Charlestoncar 365.2 mi
6h 49m$67–97Train, bus
- Take the train from Florence Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville to Winston-Salembus
- Take the bus from Winston Salem(Trans Center) to Charleston, WVbus
11h 1m$68–159
Florence to Charleston by bus
Questions & Answers
The cheapest way to get from Florence to Charleston is to bus which costs $55 - $130 and takes 10h 15m.
The fastest way to get from Florence to Charleston is to fly which takes 5h and costs $80 - $420.
No, there is no direct bus from Florence station to Charleston. However, there are services departing from Florence Bus Station and arriving at Charleston, WV via Camden and Charlotte Bus Station. The journey, including transfers, takes approximately 10h 15m.
No, there is no direct train from Florence station to Charleston station. However, there are services departing from Florence Station and arriving at Charleston Station via Alexandria. The journey, including transfers, takes approximately 17h 47m.
The distance between Florence and Charleston is 315 miles. The road distance is 367.3 miles.
The best way to get from Florence to Charleston without a car is to bus which takes 10h 15m and costs $55 - $130.
It takes approximately 5h to get from Florence to Charleston, including transfers.
Florence to Charleston bus services, operated by Greyhound USA, depart from Florence Bus Station.
Florence to Charleston train services, operated by Amtrak, depart from Florence Station.
The best way to get from Florence to Charleston is to fly which takes 5h and costs $80 - $420. Alternatively, you can bus, which costs $55 - $130 and takes 10h 15m, you could also train, which costs $230 - $550 and takes 17h 47m.
What companies run services between Florence, SC, USA and Charleston, WV, USA?
American Airlines flies from Florence Regional Airport (FLO) to Yeager Airport (CRW) 3 times a day. Alternatively, you can take a bus from Florence Bus Station to Charleston, WV via Camden and Charlotte Bus Station in around 10h 15m.
- Website
- aa.com
Flights from Florence Regional Airport to Yeager Airport via Charlotte
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $60–390
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Florence Station to Alexandria
- Ave. Duration
- 7h 37m
- Frequency
- Twice daily
- Estimated price
- $120–260
- Website
- Amtrak
Train from Alexandria to Charleston Station
- Ave. Duration
- 9h 10m
- Frequency
- 3 times a week
- Estimated price
- $110–250
- Website
- Amtrak
Train from Florence Station to Fayetteville Amtrak Station
- Ave. Duration
- 1h 21m
- Frequency
- Twice daily
- Estimated price
- $25–55
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Florence Bus Station to Camden
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $7–14
- Website
- Greyhound
Bus from Camden to Charlotte Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $11–23
- Website
- Greyhound
Bus from Charlotte Bus Station to Charleston, WV
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- Greyhound
Bus from Fayetteville to Winston-Salem
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $22–45
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Charlotte Bus Station to Charleston, WV
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $28–70
- Website
- Barons Bus
Bus from Winston Salem(Trans Center) to Charleston, WV
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $20–60
- Website
- Barons Bus
- Phone
- +1 704-348-1200
- [email protected]
- Website
- sunwaycharters.com
Bus from Fayetteville to Winston-Salem
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $23–35
- Schedules at
- sunwaycharters.com
- Passenger
- $23–35
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Florence to Charleston bus services, operated by Greyhound USA, arrive at Camden station.
Florence to Charleston train services, operated by Amtrak, arrive at Alexandria station.
Yes, the driving distance between Florence to Charleston is 367 miles. It takes approximately 6h 49m to drive from Florence to Charleston.
Book your Florence to Charleston train tickets online with Omio.
Book your Florence to Charleston bus tickets online with Omio and FlixBus.
There are 39+ hotels available in Charleston.









