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How to get fromFlorence to Cheyenneby train, plane, bus (Greyhound, Flixbus), bus, or car

Find Transport to Cheyenne

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There are 7 ways to get from Florence to Cheyenne by train, plane, bus (Greyhound, Flixbus), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Charleston International Airport, fly to Cheyenne Airport

    best
    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Cheyenne Airport (CYS)plane plane CHS - CYS
    11h 13m
    $169–709

  2. Bus, bus to Charlotte Douglas International Airport, fly to Cheyenne Airport

    cheapest
    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Cheyenne Airport (CYS)plane plane CLT - CYS
    11h 5m
    $153–635

  3. Bus

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to Cheyennebus bus
    40h 25m
    $307–494

  4. Train, bus

    1. Take the train from Florence Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Denvertrain train
    4. Take the bus from Denver Union Station to Cheyennebus bus
    2d 2h
    $616–1,365

  5. Drive  1,699.9 mi

    1. Drive from Florence to Cheyennecar car 1,699.9 mi
    27h 52m
    $311–449

  6. Train to Charleston International Airport, fly to Denver, bus

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Denver (DEN)plane plane CHS - DEN
    3. Take the bus from Denver International Airport Pickups to Warren AFBbus bus
    11h 19m
    $499–949

  7. Bus, bus to Charlotte Douglas International Airport, fly to Denver

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Denver (DEN)plane plane CLT - DEN
    4. Take the bus from Denver International Airport Pickups to Warren AFBbus bus
    12h 30m
    $223–615

Florence to Cheyenne by bus

Calendar11Weekly Buses
Duration40h 25mAverage Duration
Ticket$307Cheapest Price
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Comparing Your Travel Options

Map of how to get from Florence to Cheyenne.ExpandLaunch map view
  • Distance: 1,576.9 mi
  • Duration: 11h 13m

What companies run services between Florence, SC, USA and Cheyenne, WY, USA?

You can take a bus from Florence Bus Station to Cheyenne via Atlanta Bus Station, St Louis Bus Station, and Denver Union Station in around 40h 25m.

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