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How to get fromFlorence to Clevelandby plane, bus (Greyhound), train (Amtrak), car, bus, or train

Find Transport to Cleveland

See all options

There are 5 ways to get from Florence to Cleveland by plane, bus (Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Florence Regional Airport (FLO) to Cleveland-Hopkins International Airport (CLE)plane plane FLO - CLE
    4h 46m
    $93–495
  2. Bus

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Charlestonbus bus
    4. Take the bus from Charleston to Clevelandbus bus
    17h 10m
    $101–184
  3. Train (Amtrak)

    1. Take the train from Florence Station to Petersburg Amtrak Stationtrain train Palmetto / ...
    2. Take the train from Petersburg Amtrak Station to Cleveland Amtraktrain train Floridian
    20h 36m
    $459–719
  4. Drive  608.3 mi

    1. Drive from Florence to Clevelandcar car 608.3 mi
    11h 2m
    $111–161
  5. Bus, train

    1. Take the bus from Florence Bus Station to Raleigh Bus Stationbus bus Greyhound US0642S / ...
    2. Take the train from Raleigh Union Station to Cleveland Amtraktrain train Floridian
    22h 25m
    $431–694

Florence to Cleveland by bus

Calendar7Weekly Buses
Duration17h 10mAverage Duration
Ticket$101Cheapest Price
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Comparing Your Travel Options

What companies run services between Florence, SC, USA and Cleveland, OH, USA?

American Airlines flies from Florence Regional Airport (FLO) to Cleveland-Hopkins International Airport (CLE) once daily. Alternatively, you can take a bus from Florence Bus Station to Cleveland via Camden, Charlotte, and Charleston in around 17h 10m.

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Want to know more about travelling around United States

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Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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