There are 5 ways to get from Florence to Cleveland by plane, bus (Greyhound), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Florence Regional Airport (FLO) to Cleveland-Hopkins International Airport (CLE)plane FLO - CLE
5h 22m$93–495Bus
cheapest- Take the bus from Florence Bus Station to Camdenbus
- Take the bus from Camden to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Charleston, WVbus
- Take the bus from Charleston, WV to Cleveland, OHbus
17h 10m$91–177Train (Amtrak)
- Take the train from Florence Station to Petersburg Amtrak Stationtrain Palmetto / ...
- Take the train from Petersburg Amtrak Station to Cleveland Amtraktrain Floridian
20h 36m$211–485Drive 608.3 mi
- Drive from Florence to Clevelandcar 608.3 mi
11h 2m$111–161Train, bus
- Take the train from Florence Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville to Winston-Salembus
- Take the bus from Winston Salem to Charlestonbus
- Take the bus from Charleston to Akronbus
- Take the bus from Robert K Pfaff Transit Center - Akron to W. Prospect Ave & Superior Avebus 61
18h 52m$93–210
Florence to Cleveland by bus
Comparing Your Travel Options
The cheapest way to get from Florence to Cleveland is to bus which costs $90 - $180 and takes 17h 10m.
The fastest way to get from Florence to Cleveland is to fly which takes 5h 22m and costs $90 - $500.
No, there is no direct bus from Florence station to Cleveland. However, there are services departing from Florence Bus Station and arriving at Cleveland, OH via Camden, Charlotte Bus Station and Charleston, WV. The journey, including transfers, takes approximately 17h 10m.
No, there is no direct train from Florence station to Cleveland. However, there are services departing from Florence Station and arriving at Cleveland Amtrak via Petersburg Amtrak Station. The journey, including transfers, takes approximately 20h 36m.
The distance between Florence and Cleveland is 528 miles. The road distance is 611.9 miles.
The best way to get from Florence to Cleveland without a car is to bus which takes 17h 10m and costs $90 - $180.
It takes approximately 5h 22m to get from Florence to Cleveland, including transfers.
Florence to Cleveland bus services, operated by Greyhound USA, depart from Florence Bus Station.
Florence to Cleveland train services, operated by Amtrak, depart from Florence Station.
The best way to get from Florence to Cleveland is to fly which takes 5h 22m and costs $90 - $500. Alternatively, you can bus, which costs $90 - $180 and takes 17h 10m, you could also train, which costs $210 - $490 and takes 20h 36m.
What companies run services between Florence, SC, USA and Cleveland, OH, USA?
American Airlines flies from Florence Regional Airport (FLO) to Cleveland-Hopkins International Airport (CLE) twice daily. Alternatively, you can take a bus from Florence Bus Station to Cleveland, OH via Camden, Charlotte Bus Station, and Charleston, WV in around 17h 10m.
- Website
- aa.com
Flights from Florence Regional Airport to Cleveland-Hopkins International Airport via Charlotte
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $80–480
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Florence Station to Petersburg Amtrak Station
- Ave. Duration
- 4h 47m
- Frequency
- Twice daily
- Estimated price
- $70–160
- Website
- Amtrak
Train from Petersburg Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 14h 49m
- Frequency
- Once daily
- Estimated price
- $140–330
- Website
- Amtrak
Train from Florence Station to Fayetteville Amtrak Station
- Ave. Duration
- 1h 21m
- Frequency
- Twice daily
- Estimated price
- $21–50
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Florence Bus Station to Camden
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $7–12
- Website
- Greyhound
Bus from Camden to Charlotte Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $12–20
- Website
- Greyhound
Bus from Charlotte Bus Station to Charleston, WV
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Florence to Cleveland bus services, operated by Greyhound USA, arrive at Camden station.
Florence to Cleveland train services, operated by Amtrak, arrive at Petersburg Amtrak Station.
Yes, the driving distance between Florence to Cleveland is 612 miles. It takes approximately 11h 2m to drive from Florence to Cleveland.
Book your Florence to Cleveland train tickets online with Omio.
Book your Florence to Cleveland bus tickets online with Omio.
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