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How to get fromFlorence to Destinby plane, bus, taxi, or car

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There are 6 ways to get from Florence to Destin by plane, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Florence Regional Airport to Destin–Fort Walton Beach Airport

    best
    1. Fly from Florence Regional Airport (FLO) to Destin–Fort Walton Beach Airport (VPS)plane plane FLO - VPS
    6h 56m
    $115–417

  2. Drive 542 mi

    cheapest
    1. Drive from Florence to Destincar car 542 mi
    10h 48m
    $99–143

  3. Bus, taxi

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Mobilebus bus
    3. Take the bus from Loxley to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    16h 16m
    $245–347

  4. Fly Florence Regional Airport to Northwest Florida Beaches International Airport, taxi

    1. Fly from Florence Regional Airport (FLO) to Northwest Florida Beaches International Airport (ECP)plane plane FLO - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    7h 43m
    $210–542

  5. Bus to Myrtle Beach, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to Destin–Fort Walton Beach Airport (VPS)plane plane MYR - VPS
    6h 56m

  6. Bus, taxi via Sumter

    1. Take the bus from Florence to Sumterbus bus
    2. Take the bus from Sumter to Atlantabus bus
    3. Take the bus from Washington St at MLK Jr Dr to Newnan Park and Ridebus bus 453
    4. Take the bus from Newnan Park and Ride to Mobilebus bus
    5. Take the bus from Loxley to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    17h 54m

Florence Regional Airport (FLO) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar28Weekly Planes
Duration9h 52mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

Map of how to get from Florence to Destin.ExpandLaunch map view
  • Distance: 491.3 mi
  • Duration: 6h 56m

What companies run services between Florence, SC, USA and Destin, FL, USA?

American Airlines flies from Florence Regional Airport (FLO) to Destin–Fort Walton Beach Airport (VPS) 4 times a day.

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