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How to get fromFlorence to Floridaby bus, train (Amtrak), car, plane, bus (Greyhound), or train

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There are 10 ways to get from Florence to Florida by bus, train (Amtrak), car, plane, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Florence Bus Station to Jacksonvillebus bus FlixBus 2433
    5h 44m

  2. Bus via Sumter

    cheapest
    1. Take the bus from Florence to Sumterbus bus Ses 994 / ...
    2. Take the bus from Sumter Bus Stop to Jacksonvillebus bus Greyhound US0644S
    8h 44m
    $52–110

  3. Train (Amtrak)

    1. Take the train from Florence Station to Jacksonvilletrain train Silver Meteor
    7h
    $113–227

  4. Drive 307.4 mi

    1. Drive from Florence to Jacksonvillecar car 307.4 mi
    5h 2m
    $57–81

  5. Bus to Myrtle Beach, fly to Tampa

    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to Tampa (TPA)plane plane MYR - TPA
    5h 51m

  6. Bus to Myrtle Beach, fly to Orlando

    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to Orlando (MCO)plane plane MYR - MCO
    5h 58m

  7. Train to Charleston International Airport, fly to Fort Lauderdale–Hollywood International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    6h 51m
    $207–1,169

  8. Train to Charleston International Airport, fly to Tampa

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Tampa (TPA)plane plane CHS - TPA
    7h 13m
    $177–388

  9. Bus, bus to Charlotte Douglas International Airport, fly to Jacksonville

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Jacksonville (JAX)plane plane CLT - JAX
    8h 25m
    $90–468

  10. Bus, bus to Charlotte Douglas International Airport, fly to Tampa

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Tampa (TPA)plane plane CLT - TPA
    8h 32m
    $106–507

Myrtle Beach (MYR) to Tampa (TPA) flights

Calendar36Weekly Planes
Duration3h 39mAverage Duration
Ticket$71Cheapest Price
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Questions & Answers

Map of how to get from Florence to Florida.ExpandLaunch map view
  • Distance: 316.7 mi
  • Duration: 5h 44m

What companies run services between Florence, SC, USA and Florida, USA?

FlixBus-us operates a bus from Florence Bus Station to Jacksonville once daily, and the journey takes 5h 25m. Alternatively, Amtrak operates a train from Florence Station to Jacksonville once daily. Tickets cost $110–230 and the journey takes 6h 6m.

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Train operators
Bus operators

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