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How to get fromFlorence to Gainesvilleby bus (Greyhound), bus, train, car, plane, or train (Amtrak)

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There are 5 ways to get from Florence to Gainesville by bus (Greyhound), bus, train, car, plane, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S / ...
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus Greyhound US0670
    9h 8m
    $63–113

  2. Drive 268.7 mi

    cheapest
    1. Drive from Florence to Gainesvillecar car 268.7 mi
    4h 54m
    $49–71

  3. Bus, train

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the train from Charlotte Amtrak Station to Gainesville Stationtrain train
    9h 43m
    $85–183

  4. Train, fly, bus

    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train
    2. Fly from Fayetteville Municipal Airport (FAY) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane FAY - ATL
    3. Take the bus from Atlanta to BB Wireless - Gainesvillebus bus
    6h 51m
    $150–630

  5. Train (Amtrak)

    1. Take the train from Florence Station to Selma Stationtrain train
    2. Take the train from Selma Station to Charlotte Amtrak Stationtrain train
    3. Take the train from Charlotte Amtrak Station to Gainesville Stationtrain train
    13h 3m
    $166–366

Florence to Gainesville by bus and train

Calendar7Weekly Services
Duration9h 43mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

Map of how to get from Florence to Gainesville.ExpandLaunch map view
  • Distance: 354.3 mi
  • Duration: 9h 8m

What companies run services between Florence, SC, USA and Gainesville, GA, USA?

You can take a bus from Florence Bus Station to Gainesville via Atlanta Bus Station and Gainesville in around 9h 8m. Alternatively, you can take a train from Florence Station to Gainesville Station via Selma Station and Charlotte Amtrak Station in around 13h 3m.

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Need to know: Greyhound

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