There are 5 ways to get from Florence to Gatlinburg by plane, taxi, bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, taxi
best- Fly from Florence Regional Airport (FLO) to Mcghee Tyson Airport (TYS)plane FLO - TYS
- Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi
4h 45m$260–772Drive 303.5 mi
cheapest- Drive from Florence to Gatlinburgcar 303.5 mi
5h 38m$56–80Bus, drive (Greyhound)
- Take the bus from Florence Bus Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Asheville, NCbus
- Drive from Asheville, NC to Gatlinburgcar
11h 18m$72–139Train, bus, drive via Fayetteville
- Take the train from Florence Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville Bus Station to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Asheville, NCbus
- Drive from Asheville, NC to Gatlinburgcar
11h 59m$85–155Train, bus, drive
- Take the train from Florence Station to Selma Stationtrain
- Take the train from Selma Station to Greensborotrain
- Take the bus from Greensboro Bus Stop to Asheville, NCbus
- Drive from Asheville, NC to Gatlinburgcar
12h 2m$117–232
Florence Regional Airport (FLO) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Florence to Gatlinburg is to drive which costs $55 - $80 and takes 5h 38m.
The fastest way to get from Florence to Gatlinburg is to fly and taxi which takes 4h 45m and costs $260 - $800.
The distance between Florence and Gatlinburg is 309 miles. The road distance is 305.2 miles.
It takes approximately 4h 45m to get from Florence to Gatlinburg, including transfers.
Yes, the driving distance between Florence to Gatlinburg is 305 miles. It takes approximately 5h 38m to drive from Florence to Gatlinburg.
There are 7076+ hotels available in Gatlinburg.
What companies run services between Florence, SC, USA and Gatlinburg, TN, USA?
There is no direct connection from Florence to Gatlinburg. However, you can take the taxi to Florence Regional Airport (FLO) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Gatlinburg. Alternatively, you can take a bus from Florence Bus Station to Gatlinburg via Raleigh Bus Station and Asheville, NC in around 11h 18m.
- Website
- aa.com
Flights from Florence Regional Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $80–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Florence Station to Fayetteville Amtrak Station
- Ave. Duration
- 1h 21m
- Frequency
- Twice daily
- Estimated price
- $26–55
- Website
- Amtrak
Train from Florence Station to Selma Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Amtrak
Train from Selma Station to Greensboro
- Ave. Duration
- 2h 34m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Florence Bus Station to Raleigh Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- 4 times a day
- Estimated price
- $23–45
- Website
- Greyhound
Bus from Raleigh Bus Station to Asheville, NC
- Ave. Duration
- 5h 10m
- Frequency
- Twice daily
- Estimated price
- $35–75
- Website
- Greyhound
Bus from Fayetteville Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 4h 10m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Asheville, NC
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Greyhound
Bus from Greensboro Bus Stop to Asheville, NC
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $26–50
- Website
- Greyhound
- Phone
- +1 704-348-1200
- [email protected]
- Website
- sunwaycharters.com
Bus from Fayetteville Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $23–35
- Schedules at
- sunwaycharters.com
- Passenger
- $23–35
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide





