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How to get fromFlorence to Illinoisby bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

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There are 12 ways to get from Florence to Illinois by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, bus to Charlotte Douglas International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD)plane plane CLT - ORD
    8h 29m
    $145–458

  2. Bus, bus to Charlotte Douglas International Airport, fly to Chicago Midway International Airport

    cheapest
    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    8h 7m
    $105–488

  3. Bus

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S / ...
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    23h 40m
    $156–296

  4. Train (Amtrak)

    1. Take the train from Florence Station to Petersburg Amtrak Stationtrain train Palmetto / ...
    2. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train Floridian
    27h 28m
    $378–778

  5. Drive 843.4 mi

    1. Drive from Florence to Chicagocar car 843.4 mi
    15h 14m
    $154–223

  6. Bus, bus to Charlotte Douglas International Airport, fly to Peoria International Airport

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Peoria International Airport (PIA)plane plane CLT - PIA
    8h 44m
    $109–504

  7. Bus, bus to Columbia, fly to Chicago O'Hare International Airport

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Columbia, SCbus bus
    3. Fly from Columbia (CAE) to Chicago O'Hare International Airport (ORD)plane plane CAE - ORD
    9h 7m
    $171–813

  8. Train, bus to Myrtle Beach, fly to Chicago Midway International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW)plane plane MYR - MDW
    8h 41m
    $124–461

  9. Train, bus to Myrtle Beach, fly to Chicago O'Hare International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD)plane plane MYR - ORD
    9h 11m
    $114–411

  10. Bus, bus to Charlotte Douglas International Airport, fly to South Bend, train

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to South Bend (SBN)plane plane CLT - SBN
    4. Take the train from South Bend Airport to Van Buren St.train train
    10h 27m
    $146–708

  11. Bus, bus to Charlotte Douglas International Airport, fly to Lambert–St. Louis International Airport, train

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    4. Take the train from St. Louis to Springfieldtrain train
    10h 47m
    $166–761

  12. Bus, train

    1. Take the bus from Florence Bus Station to Raleigh Bus Stationbus bus Greyhound US0642S / ...
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train Floridian
    29h 15m
    $365–796

Florence to Illinois by bus

Calendar14Weekly Buses
Duration23h 40mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

Map of how to get from Florence to Illinois.ExpandLaunch map view
  • Distance: 752.6 mi
  • Duration: 8h 29m

What companies run services between Florence, SC, USA and Illinois, USA?

You can take a bus from Florence Bus Station to Chicago Bus Station via Atlanta Bus Station in around 23h 40m. Alternatively, you can take a train from Florence Station to Chicago Union Station via Petersburg Amtrak Station in around 27h 28m.

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Train operators
Bus operators

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