Rome2Rio

How to get fromFlorence to Indianaby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Find Transport to Indiana

See all options

There are 5 ways to get from Florence to Indiana by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Florence Regional Airport (FLO) to Indianapolis (IND)plane plane FLO - IND
    4h 49m
    $102–564
  2. Bus

    cheapest
    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Columbusbus bus
    4. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Richmond, INbus bus
    5. Take the bus from Richmond Bsb, IN to Indianapolis, INbus bus
    20h 50m
    $81–217
  3. Bus via Atlanta

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S / ...
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    19h 20m
    $127–203
  4. Train, bus (Amtrak)

    1. Take the train from Florence Station to Richmond Staples Mill Road Amtrak Stationtrain train
    2. Take the bus from Richmond Staples Mill Road Station to Charlottesville Amtrak Stationbus bus
    3. Take the train from Charlottesville to Indianapolistrain train
    24h 30m
    $244–546
  5. Drive  660.9 mi

    1. Drive from Florence to Indianapoliscar car 660.9 mi
    12h 17m
    $121–175

Florence to Indiana by bus

Calendar12Weekly Buses
Duration19h 20mAverage Duration
Ticket$127Cheapest Price
See schedules

Comparing Your Travel Options

What companies run services between Florence, SC, USA and Indiana, USA?

American Airlines flies from Florence Regional Airport (FLO) to Indianapolis (IND) twice daily. Alternatively, you can take a bus from Florence Bus Station to Indianapolis via Atlanta Bus Station in around 19h 20m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There