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How to get fromFlorence to Key Largoby train, plane, shuttle, bus, bus (Greyhound, Flixbus), or car

Find Transport to Key Largo

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There are 9 ways to get from Florence to Key Largo by train, plane, shuttle, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Charleston International Airport, fly to Miami International Airport, shuttle

    best
    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane plane CHS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    8h 23m
    $619–1,190

  2. Bus

    cheapest
    1. Take the bus from Florence Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    20h 25m
    $120–219

  3. Train, bus

    1. Take the train from Florence Station to Miami Amtrak Stationtrain train Silver Meteor
    2. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus bus 301
    19h 28m
    $211–453

  4. Drive  713 mi

    1. Drive from Florence to Key Largocar car 713 mi
    11h 51m
    $131–188

  5. Train to Charleston International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    8h 46m
    $379–1,310

  6. Bus, bus to Charlotte Douglas International Airport, fly to Miami International Airport, shuttle

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Miami International Airport (MIA)plane plane CLT - MIA
    4. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    9h 54m
    $251–547

  7. Train, bus to Wilmington International Airport, fly to Miami International Airport, shuttle

    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train
    2. Take the bus from Fayetteville Bus Station to Wilmington Cape Fear Public Transitbus bus
    3. Fly from Wilmington International Airport (ILM) to Miami International Airport (MIA)plane plane ILM - MIA
    4. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    10h 4m
    $217–602

  8. Bus, bus to Charlotte Douglas International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CLT - FLL
    4. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    10h 20m
    $221–537

  9. Train, bus to Myrtle Beach, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MYR - FLL
    4. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    10h 36m
    $310–667

Florence to Key Largo by train, foot, and bus

Calendar7Weekly Services
Duration19h 28mAverage Duration
Ticket$211Cheapest Price
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Questions & Answers

Map of how to get from Florence to Key Largo.ExpandLaunch map view
  • Distance: 648.4 mi
  • Duration: 8h 23m

What companies run services between Florence, SC, USA and Key Largo, FL, USA?

You can take a bus from Florence Bus Station to Key Largo Bus Stop via Fayetteville Bus Station and Miami Airport Station in around 20h 25m.

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Bus operators

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