There are 6 ways to get from Florence to Key West by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Florence Regional Airport
best- Fly from Florence Regional Airport (FLO) to Key West International Airport (EYW)plane FLO - EYW
6h 29m$91–365Bus
- Take the bus from Florence Bus Station to Savannah Bus Stationbus
- Take the bus from Savannah Bus Station to Ft Lauderdale Broward Park & Ridebus
- Take the bus from Ft Lauderdale Broward Park & Ride to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
22h 24mTrain, bus
- Take the train from Florence Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
23h 7m$266–533Drive 810.1 mi
- Drive from Florence to Key Westcar 810.1 mi
14h 7m$148–214Bus to Myrtle Beach, fly
- Take the bus from Florence to Myrtle Beachbus
- Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)plane MYR - EYW
7h 17mTrain to Fayetteville Municipal Airport, fly
- Take the train from Florence Station to Fayetteville Amtrak Stationtrain
- Fly from Fayetteville Municipal Airport (FAY) to Key West International Airport (EYW)plane FAY - EYW
6h 53m$125–438
Florence Regional Airport (FLO) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Florence to Key West is to drive which costs $140 - $220 and takes 14h 7m.
The fastest way to get from Florence to Key West is to fly which takes 6h 29m and costs $90 - $370.
No, there is no direct bus from Florence station to Key West. However, there are services departing from Florence Bus Station and arriving at N Roosevelt & 3rd Street via Savannah Bus Station, Ft Lauderdale Broward Park & Ride, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 22h 24m.
The distance between Florence and Key West is 685 miles. The road distance is 814.8 miles.
The best way to get from Florence to Key West without a car is to bus which takes 22h 24m and costs .
It takes approximately 6h 29m to get from Florence to Key West, including transfers.
Florence to Key West bus services, operated by FlixBus-us, depart from Florence Bus Station.
The best way to get from Florence to Key West is to fly which takes 6h 29m and costs $90 - $370. Alternatively, you can bus, which costs and takes 22h 24m.
Florence to Key West bus services, operated by FlixBus-us, arrive at Savannah Bus Station.
Yes, the driving distance between Florence to Key West is 815 miles. It takes approximately 14h 7m to drive from Florence to Key West.
What companies run services between Florence, SC, USA and Key West, FL, USA?
American Airlines and Breeze Airways fly from Florence Regional Airport (FLO) to Key West International Airport (EYW) twice daily. Alternatively, you can take a bus from Florence Bus Station to N Roosevelt & 3rd Street via Savannah Bus Station, Ft Lauderdale Broward Park & Ride, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 22h 24m.
- Website
- aa.com
Flights from Florence Regional Airport to Key West International Airport via Charlotte
- Ave. Duration
- 10h 42m
- When
- Every day
- Estimated price
- $70–340
Flights from Myrtle Beach to Key West International Airport via Charlotte
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $65–320
Flights from Fayetteville Municipal Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $70–350
- Website
- delta.com
Flights from Myrtle Beach to Key West International Airport via Atlanta
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $70–330
Flights from Fayetteville Municipal Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $75–370
- Website
- flybreeze.com
Flights from Florence Regional Airport to Key West International Airport via Charlotte, Orlando
- Ave. Duration
- 6h 20m
- When
- Sunday
- Estimated price
- $70–340
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Florence Station to Hollywood Amtrak Station
- Ave. Duration
- 15h 3m
- Frequency
- Once daily
- Estimated price
- $240–490
- Website
- https://www.amtrak.com/home.html
Train from Florence Station to Fayetteville Amtrak Station
- Ave. Duration
- 1h 21m
- Frequency
- Twice daily
- Estimated price
- $26–55
- Website
- https://www.amtrak.com/home.html
- Website
- flixbus.com
Bus from Florence Bus Station to Savannah Bus Station
- Ave. Duration
- 3h
- Frequency
- Once daily
- Schedules at
- flixbus.com
Bus from Ft Lauderdale Broward Park & Ride to Miami Airport Station
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Schedules at
- flixbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Savannah Bus Station to Ft Lauderdale Broward Park & Ride
- Ave. Duration
- 9h 45m
- Frequency
- 4 times a week
- Estimated price
- $75–130
- Schedules at
- flixbus.com
Bus from Ft Lauderdale Broward Park & Ride to Miami Airport Station
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- $4–8
- Schedules at
- flixbus.com
- Website
- greyhound.com
Bus from Ft Lauderdale Broward Park & Ride to Miami Airport Station
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Schedules at
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Ft Lauderdale Broward Park & Ride to Miami Airport Station
- Ave. Duration
- 50 min
- Frequency
- 4 times a day
- Estimated price
- $4–9
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Website
- example.com
Bus from Florence to Myrtle Beach
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Schedules at
- example.com
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