Rome2Rio

How to get fromFlorence to Largoby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or bus (Greyhound)

Find Transport to Largo

See all options

There are 6 ways to get from Florence to Largo by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Florence Regional Airport

    best
    1. Fly from Florence Regional Airport (FLO) to Tampa (TPA)plane plane FLO - TPA
    6h 15m
    $83–395

  2. Bus

    1. Take the bus from Florence Bus Station to Orlando Bus Stationbus bus FlixBus 2433
    2. Take the bus from Orlando Bus Station to Tampa Bus Stationbus bus FlixBus N2411 / ...
    13h 27m

  3. Train (Amtrak)

    1. Take the train from Florence Station to Kissimmee Amtrak Stationtrain train Silver Meteor
    2. Take the train from Kissimmee Amtrak Station to Tampatrain train Floridian
    15h 23m
    $197–388

  4. Drive 507 mi

    1. Drive from Florence to Largocar car 507 mi
    9h 21m
    $93–134

  5. Bus to Myrtle Beach, fly

    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to Tampa (TPA)plane plane MYR - TPA
    6h 28m

  6. Bus via Jacksonville

    1. Take the bus from Florence to Sumterbus bus
    2. Take the bus from Sumter Bus Stop to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Tampa Bus Stationbus bus
    18h 39m

Florence Regional Airport (FLO) to Tampa (TPA) flights

Calendar8Weekly Planes
Duration4h 46mAverage Duration
Ticket$73Cheapest Price
See schedules

Questions & Answers

Map of how to get from Florence to Largo.ExpandLaunch map view
  • Distance: 482.3 mi
  • Duration: 6h 15m

What companies run services between Florence, SC, USA and Largo, FL, USA?

American Airlines flies from Florence Regional Airport (FLO) to Tampa (TPA) once daily. Alternatively, you can take a bus from Florence Bus Station to Ulmerton Park N Ride Lot via Orlando Bus Station, Tampa Bus Station, and Marion Transit Parking Lot in around 13h 27m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers