There are 4 ways to get from Florence to Lewes by plane, taxi, train, bus, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, taxi
best- Fly from Florence Regional Airport (FLO) to Salisbury–Ocean City–Wicomico Regional Airport (SBY)plane FLO - SBY
- Take the taxi from Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Lewestaxi
6h 42m$205–582Bus
cheapest- Take the bus from Florence Bus Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Baltimore Downtown Bus Stationbus
- Take the bus from Baltimore Downtown Bus Station to Wilmington Bus Stationbus
- Take the bus from Wilmington Tc to Lewes Transit Centerbus 305
16h 10m$79–159Train, bus
- Take the train from Florence Station to Wilmingtontrain Palmetto / ...
- Take the bus from Wilmington Tc to Lewes Transit Centerbus 305
14h 7m$167–348Drive 459.2 mi
- Drive from Florence to Lewescar 459.2 mi
9h 6m$84–121
Florence to Lewes by train and bus
Questions & Answers
The cheapest way to get from Florence to Lewes is to drive which costs $80 - $130 and takes 9h 6m.
The fastest way to get from Florence to Lewes is to fly and taxi which takes 6h 42m and costs $200 - $600.
No, there is no direct bus from Florence station to Lewes. However, there are services departing from Florence Bus Station and arriving at Savannah Rd @ 3Rd St via Raleigh Bus Station, Baltimore Downtown Bus Station, Wilmington Tc and Lewes Transit Center. The journey, including transfers, takes approximately 16h 10m.
The distance between Florence and Lewes is 416 miles. The road distance is 461.9 miles.
The best way to get from Florence to Lewes without a car is to train and bus which takes 14h 7m and costs $160 - $350.
It takes approximately 6h 42m to get from Florence to Lewes, including transfers.
Florence to Lewes bus services, operated by Greyhound USA, depart from Florence Bus Station.
Florence to Lewes bus services, operated by Greyhound USA, arrive at Raleigh Bus Station.
Yes, the driving distance between Florence to Lewes is 462 miles. It takes approximately 9h 6m to drive from Florence to Lewes.
There are 422+ hotels available in Lewes.
What companies run services between Florence, SC, USA and Lewes, DE, USA?
You can take a bus from Florence Bus Station to Savannah Rd @ 3Rd St via Raleigh Bus Station, Baltimore Downtown Bus Station, Wilmington Bus Station, Wilmington Tc, and Lewes Transit Center in around 16h 10m.
- Website
- aa.com
Flights from Florence Regional Airport to Salisbury–Ocean City–Wicomico Regional Airport via Charlotte
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $65–400
Flights from Florence Regional Airport to Salisbury–Ocean City–Wicomico Regional Airport via Charlotte, Philadelphia
- Ave. Duration
- 8h 21m
- When
- Every day
- Estimated price
- $80–440
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Florence Station to Wilmington
- Ave. Duration
- 10h 32m
- Frequency
- Twice daily
- Estimated price
- $160–340
- Website
- Amtrak
- Phone
- +1 800-652-3278
- Website
- DART
Bus from Wilmington Tc to Lewes Transit Center
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Bus from Wilmington Tc to Lewes Transit Center
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Florence Bus Station to Raleigh Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Greyhound
Bus from Raleigh Bus Station to Baltimore Downtown Bus Station
- Ave. Duration
- 6h
- Frequency
- 5 times a day
- Estimated price
- $40–85
- Website
- Greyhound
Bus from Baltimore Downtown Bus Station to Wilmington Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $10–21
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Raleigh Bus Station to Baltimore Downtown Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- Twice daily
- Estimated price
- $45–75
- Schedules at
- Flixbus USA
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