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How to get fromFlorence to Lexingtonby plane, bus (Greyhound), car, or bus

Find Transport to Lexington

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There are 5 ways to get from Florence to Lexington by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Florence Regional Airport

    best
    1. Fly from Florence Regional Airport (FLO) to Blue Grass Airport (LEX)plane plane FLO - LEX
    6h 34m
    $122–714

  2. Drive 481.4 mi

    cheapest
    1. Drive from Florence to Lexingtoncar car 481.4 mi
    9h 9m
    $88–127

  3. Bus via Atlanta

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S / ...
    2. Take the bus from Atlanta Bus Station to Lexington Bus Stopbus bus Greyhound US0110
    15h 32m
    $134–241

  4. Bus to Myrtle Beach, fly

    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to Blue Grass Airport (LEX)plane plane MYR - LEX
    8h 42m

  5. Bus

    1. Take the bus from Florence to Charlottebus bus
    2. Take the bus from Charlotte to Columbusbus bus
    3. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Cincinnati, OHbus bus
    4. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus
    22h 43m

Florence Regional Airport (FLO) to Blue Grass Airport (LEX) flights

Calendar21Weekly Planes
Duration5h 49mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

Map of how to get from Florence to Lexington.ExpandLaunch map view
  • Distance: 396.3 mi
  • Duration: 6h 34m

What companies run services between Florence, SC, USA and Lexington, KY, USA?

American Airlines flies from Florence Regional Airport (FLO) to Blue Grass Airport (LEX) 3 times a day. Alternatively, you can take a bus from Florence Bus Station to Lexington via Atlanta Bus Station and Lexington Bus Stop in around 15h 32m.

Airlines
Bus operators

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