There are 4 ways to get from Florence to Lexington by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Florence Regional Airport
best- Fly from Florence Regional Airport (FLO) to Blue Grass Airport (LEX)plane FLO - LEX
6h 2m$62–354Bus, drive
- Take the bus from Florence Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Evansville Bus Stationbus
- Take the bus from Evansville, IN to Corydon, INbus
- Drive from Middletown Station @ Target to Lexingtoncar
22h 4m$227–391Drive 481.4 mi
- Drive from Florence to Lexingtoncar 481.4 mi
9h 9m$83–119Bus to Myrtle Beach, fly
- Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus
- Fly from Myrtle Beach (MYR) to Blue Grass Airport (LEX)plane MYR - LEX
8h 44m$75–344
Florence Regional Airport (FLO) to Blue Grass Airport (LEX) flights
Comparing Your Travel Options
The cheapest way to get from Florence to Lexington is to drive which costs $80 - $120 and takes 9h 9m.
The fastest way to get from Florence to Lexington is to fly which takes 6h 2m and costs $60 - $360.
The distance between Florence and Lexington is 399 miles. The road distance is 484.2 miles.
It takes approximately 6h 2m to get from Florence to Lexington, including transfers.
Yes, the driving distance between Florence to Lexington is 484 miles. It takes approximately 9h 9m to drive from Florence to Lexington.
There are 183+ hotels available in Lexington.
What companies run services between Florence, SC, USA and Lexington, KY, USA?
American Airlines flies from Florence Regional Airport (FLO) to Blue Grass Airport (LEX) 3 times a day.
- Website
- aa.com
Flights from Florence Regional Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $50–340
Flights from Myrtle Beach to Blue Grass Airport via Charlotte
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $50–310
- Website
- delta.com
Flights from Myrtle Beach to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $60–340
Flights from Myrtle Beach to Blue Grass Airport via Detroit
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $75–390
- Website
- united.com
Flights from Myrtle Beach to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $85–410
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- 4 times a day
- Estimated price
- $55–85
- Website
- Greyhound
Bus from Atlanta Bus Station to Evansville Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Twice daily
- Estimated price
- $70–110
- Website
- Greyhound
Bus from Florence Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $12–19
- Website
- Greyhound
- Phone
- +1 502-368-5644 x 135
- Website
- Miller Transportation
Bus from Evansville, IN to Corydon, IN
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $30–100
- Website
- Miller Transportation
Want to know more about travelling around United States
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