What is the cheapest way to get from Florence to Lexington?

The cheapest way to get from Florence to Lexington is to drive which costs $85 - $130 and takes 9h 9m.

What is the fastest way to get from Florence to Lexington?

The fastest way to get from Florence to Lexington is to fly and drive which takes 5h 31m and costs $120 - $700.

How far is it from Florence to Lexington?

The distance between Florence and Lexington is 519 miles. The road distance is 484.2 miles.

How long does it take to get from Florence to Lexington?

It takes approximately 5h 31m to get from Florence to Lexington, including transfers.

Can I drive from Florence to Lexington?

Yes, the driving distance between Florence to Lexington is 484 miles. It takes approximately 9h 9m to drive from Florence to Lexington.

Where can I stay near Lexington?

There are 179+ hotels available in Lexington.

Florence to Lexington - 5 ways to travel via plane, car, and bus

How to get fromFlorence to Lexington

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There are 5 ways to get from Florence to Lexington by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly Florence Regional Airport to Louisville International Airport, drive
best
1. Fly from Florence Regional Airport (FLO) to Louisville International Airport (SDF)plane FLO - SDF
2. Drive from Louisville-Airport-SDF to Lexingtoncar
5h 31m
$124–683
Fly Florence Regional Airport to Blue Grass Airport
cheapest
1. Fly from Florence Regional Airport (FLO) to Blue Grass Airport (LEX)plane FLO - LEX
6h 2m
$62–354
Bus, drive
1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus
2. Take the bus from Atlanta Bus Station to Evansville Bus Stationbus
3. Take the bus from Evansville, IN to Corydon, INbus
4. Drive from Middletown Station @ Target to Lexingtoncar
22h 4m
$227–392
Drive 481.4 mi
1. Drive from Florence to Lexingtoncar 481.4 mi
9h 9m
$86–123
Bus to Myrtle Beach, fly to Blue Grass Airport
1. Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus
2. Fly from Myrtle Beach (MYR) to Blue Grass Airport (LEX)plane MYR - LEX
8h 44m
$75–344

Florence Regional Airport (FLO) to Louisville International Airport (SDF) flights

15Weekly Planes

5h 46mAverage Duration

$109Cheapest Price

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Comparing Your Travel Options

Map of how to get from Florence to Lexington.

Launch map view

Distance: 515.7 mi
Duration: 5h 31m

What companies run services between Florence, SC, USA and Lexington, KY, USA?

American Airlines flies from Florence Regional Airport (FLO) to Blue Grass Airport (LEX) 3 times a day.

Airlines

Bus operators

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How to get fromFlorence to Lexingtonby plane, car, or bus

There are 5 ways to get from Florence to Lexington by plane, car, or bus

Fly Florence Regional Airport to Louisville International Airport, drive

Fly Florence Regional Airport to Blue Grass Airport

Bus, drive

Drive 481.4 mi

Bus to Myrtle Beach, fly to Blue Grass Airport