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How to get fromFlorence to Los Angelesby plane, bus, train, bus (Greyhound, Flixbus), car, or train (Amtrak)

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There are 6 ways to get from Florence to Los Angeles by plane, bus, train, bus (Greyhound, Flixbus), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Los Angeles International Airport

    best
    1. Fly from Florence Regional Airport (FLO) to Los Angeles International Airport (LAX)plane plane FLO - LAX
    8h 10m
    $147–575

  2. Bus, train

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Houston - Telephone Rdbus bus
    3. Take the train from Houston to Los Angelestrain train
    2d 11h
    $680–1,410

  3. Bus

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    2d 12h
    $410–806

  4. Drive 2,453.8 mi

    1. Drive from Florence to Los Angelescar car 2,453.8 mi
    38h 46m
    $448–647

  5. Fly to John Wayne Airport Orange County

    1. Fly from Florence Regional Airport (FLO) to John Wayne Airport Orange County (SNA)plane plane FLO - SNA
    13h 38m
    $231–883

  6. Train (Amtrak)

    1. Take the train from Florence Station to Selma Stationtrain train
    2. Take the train from Selma Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Los Angelestrain train
    3d 1h
    $1,091–2,355

Florence to Los Angeles by bus

Calendar7Weekly Buses
Duration2d 12hAverage Duration
Ticket$410Cheapest Price
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Questions & Answers

Map of how to get from Florence to Los Angeles.ExpandLaunch map view
  • Distance: 2,217.6 mi
  • Duration: 8h 10m

What companies run services between Florence, SC, USA and Los Angeles, CA, USA?

American Airlines flies from Florence Regional Airport (FLO) to Los Angeles International Airport (LAX) 4 times a day. Alternatively, you can take a bus from Florence Bus Station to Los Angeles Union Station via Atlanta Bus Station and St Louis Bus Station in around 2d 12h.

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Want to know more about travelling around United States

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