What is the cheapest way to get from Florence to Louisville?

The cheapest way to get from Florence to Louisville is to drive which costs $100 - $150 and takes 10h 46m.

What is the fastest way to get from Florence to Louisville?

The fastest way to get from Florence to Louisville is to fly which takes 6h 29m and costs $90 - $500.

Is there a direct bus between Florence and Louisville?

No, there is no direct bus from Florence station to Louisville. However, there are services departing from Florence Bus Station and arriving at Louisville, KY via Atlanta Bus Station and Nashville. The journey, including transfers, takes approximately 16h 35m.

How far is it from Florence to Louisville?

The distance between Florence and Louisville is 445 miles. The road distance is 551.3 miles.

How do I travel from Florence to Louisville without a car?

The best way to get from Florence to Louisville without a car is to bus which takes 16h 35m and costs $110 - $220.

How long does it take to get from Florence to Louisville?

It takes approximately 6h 29m to get from Florence to Louisville, including transfers.

Where do I catch the Florence to Louisville bus from?

Florence to Louisville bus services, operated by Greyhound USA, depart from Florence Bus Station.

Bus or fly from Florence to Louisville?

The best way to get from Florence to Louisville is to fly which takes 6h 29m and costs $90 - $500. Alternatively, you can bus, which costs $110 - $220 and takes 16h 35m.

Where does the Florence to Louisville bus arrive?

Florence to Louisville bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.

Can I drive from Florence to Louisville?

Yes, the driving distance between Florence to Louisville is 551 miles. It takes approximately 10h 46m to drive from Florence to Louisville.

How do I get a bus ticket from Florence to Louisville?

Book your Florence to Louisville bus tickets online with Omio.

Where can I stay near Louisville?

There are 606+ hotels available in Louisville.

Florence to Louisville - 4 ways to travel via train, plane, bus, and car

How to get fromFlorence to Louisville

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There are 4 ways to get from Florence to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Florence Regional Airport (FLO) to Louisville International Airport (SDF)plane FLO - SDF
6h 29m
$91–495
Bus
1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus
2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus
3. Take the bus from Nashville to Louisville, KYbus
16h 35m
$110–211
Drive 548.1 mi
1. Drive from Florence to Louisvillecar 548.1 mi
10h 46m
$100–145
Train, bus
1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain
2. Take the bus from Fayetteville to Winston-Salembus
3. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus
4. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus
21h 46m
$105–249

Florence to Louisville by bus

14Weekly Buses

16h 35mAverage Duration

$110Cheapest Price

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Questions & Answers

Map of how to get from Florence to Louisville.

Launch map view

Distance: 442.4 mi
Duration: 6h 29m

What companies run services between Florence, SC, USA and Louisville, KY, USA?

American Airlines flies from Florence Regional Airport (FLO) to Louisville International Airport (SDF) twice daily. Alternatively, you can take a bus from Florence Bus Station to Louisville, KY via Atlanta Bus Station and Nashville in around 16h 35m.

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