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How to get fromFlorence to Memphisby plane, bus (Greyhound), car, bus, or train

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There are 6 ways to get from Florence to Memphis by plane, bus (Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Florence Regional Airport

    best
    1. Fly from Florence Regional Airport (FLO) to Memphis (MEM)plane plane FLO - MEM
    6h 8m
    $131–663

  2. Bus

    cheapest
    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S / ...
    2. Take the bus from Atlanta Bus Station to Memphis Bus Stationbus bus Greyhound US0610
    16h 52m
    $108–210

  3. Drive 667.7 mi

    1. Drive from Florence to Memphiscar car 667.7 mi
    11h 6m
    $122–176

  4. Bus to Myrtle Beach, fly

    1. Take the bus from Florence to Myrtle Beachbus bus
    2. Fly from Myrtle Beach (MYR) to Memphis (MEM)plane plane MYR - MEM
    8h 9m

  5. Train to Fayetteville Municipal Airport, fly

    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train
    2. Fly from Fayetteville Municipal Airport (FAY) to Memphis (MEM)plane plane FAY - MEM
    7h 50m
    $165–726

  6. Bus via Sumter

    1. Take the bus from Florence to Sumterbus bus
    2. Take the bus from Sumter to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to Memphis Bus Stationbus bus
    17h 52m

Florence to Memphis by bus

Calendar28Weekly Buses
Duration16h 52mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Florence to Memphis.ExpandLaunch map view
  • Distance: 601.1 mi
  • Duration: 6h 8m

What companies run services between Florence, SC, USA and Memphis, TN, USA?

American Airlines flies from Florence Regional Airport (FLO) to Memphis (MEM) once daily. Alternatively, you can take a bus from Florence Bus Station to 3RD STREET at EXCHANGE AVENUE via Atlanta Bus Station and Airways Transit Center in around 16h 52m.

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