There are 5 ways to get from Florence to Milwaukee by plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Florence Regional Airport (FLO) to General Mitchell International Airport (MKE)plane FLO - MKE
6h 46m$113–615Bus
- Take the bus from Florence Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
26h 20m$177–293Train (Amtrak)
- Take the train from Florence Station to Selma Stationtrain
- Take the train from Selma Station to Raleigh Union Stationtrain
- Take the train from Raleigh Union Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Milwaukeetrain
31h 52m$683–1,161Drive 931.2 mi
- Drive from Florence to Milwaukeecar 931.2 mi
16h 56m$170–246Train, bus
- Take the train from Florence Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville to Winston-Salembus
- Take the bus from Winston Salem to Columbusbus
- Take the bus from Columbus to Milwaukee Intermodal Stationbus
27h 25m$182–308
Florence to Milwaukee by bus
Comparing Your Travel Options
The cheapest way to get from Florence to Milwaukee is to drive which costs $170 - $250 and takes 16h 56m.
The fastest way to get from Florence to Milwaukee is to fly which takes 6h 46m and costs $110 - $650.
No, there is no direct bus from Florence station to Milwaukee station. However, there are services departing from Florence Bus Station and arriving at Milwaukee Intermodal Station via Atlanta Bus Station and Chicago Bus Station. The journey, including transfers, takes approximately 26h 20m.
No, there is no direct train from Florence station to Milwaukee. However, there are services departing from Florence Station and arriving at Milwaukee via Selma Station, Raleigh Union Station and Chicago Union Station. The journey, including transfers, takes approximately 31h 52m.
The distance between Florence and Milwaukee is 762 miles. The road distance is 936.7 miles.
The best way to get from Florence to Milwaukee without a car is to bus which takes 26h 20m and costs $170 - $300.
It takes approximately 6h 46m to get from Florence to Milwaukee, including transfers.
Florence to Milwaukee bus services, operated by Greyhound USA, depart from Florence Bus Station.
Florence to Milwaukee train services, operated by Amtrak, depart from Florence Station.
The best way to get from Florence to Milwaukee is to fly which takes 6h 46m and costs $110 - $650. Alternatively, you can bus, which costs $170 - $300 and takes 26h 20m, you could also train, which costs $650 - $1,200 and takes 31h 52m.
What companies run services between Florence, SC, USA and Milwaukee, WI, USA?
American Airlines flies from Florence Regional Airport (FLO) to General Mitchell International Airport (MKE) 3 times a day. Alternatively, you can take a bus from Florence Bus Station to Milwaukee Intermodal Station via Atlanta Bus Station and Chicago Bus Station in around 26h 20m.
- Website
- aa.com
Flights from Florence Regional Airport to General Mitchell International Airport via Charlotte
- Ave. Duration
- 7h 14m
- When
- Every day
- Estimated price
- $100–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Florence Station to Selma Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $70–120
- Website
- Amtrak
Train from Selma Station to Raleigh Union Station
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $15–25
- Website
- Amtrak
Train from Raleigh Union Station to Chicago Union Station
- Ave. Duration
- 24h 28m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Florence Station to Fayetteville Amtrak Station
- Ave. Duration
- 1h 21m
- Frequency
- Twice daily
- Estimated price
- $45–70
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 16h
- Frequency
- 4 times a day
- Estimated price
- $120–190
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $15–24
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 16h 10m
- Frequency
- Twice daily
- Estimated price
- $110–170
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
Bus from Columbus to Milwaukee Intermodal Station
- Ave. Duration
- 10h
- Frequency
- 6 times a week
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from Fayetteville to Winston-Salem
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $24–35
- Schedules at
- Sunway Charters
- Passenger
- $24–35
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Winston Salem to Columbus
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Barons Bus
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Florence to Milwaukee bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Milwaukee is 1h behind Florence. It is currently 5:57 PM in Florence and 4:57 PM in Milwaukee.
Florence to Milwaukee train services, operated by Amtrak, arrive at Selma Station.
Yes, the driving distance between Florence to Milwaukee is 937 miles. It takes approximately 16h 56m to drive from Florence to Milwaukee.
Book your Florence to Milwaukee train tickets online with Omio.
Book your Florence to Milwaukee bus tickets online with Omio and FlixBus.
There are 253+ hotels available in Milwaukee.










