There are 6 ways to get from Florence to Mississippi by plane, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Memphis
best- Fly from Florence Regional Airport (FLO) to Memphis (MEM)plane FLO - MEM
4h 48m$152–689Bus (Greyhound)
cheapest- Take the bus from Florence Bus Station to Atlanta Bus Stationbus Greyhound US0641S / ...
- Take the bus from Atlanta Bus Station to Jacksonbus Greyhound US0604
15h 20m$100–206Train (Amtrak)
- Take the train from Florence Station to Selma Stationtrain
- Take the train from Selma Station to Greensborotrain
- Take the train from Greensboro to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Jacksontrain
33h 8m$412–891Drive 671.3 mi
- Drive from Florence to Jacksoncar 671.3 mi
10h 58m$123–177Fly to Gulfport-Biloxi Regional Airport
- Fly from Florence Regional Airport (FLO) to Gulfport-Biloxi Regional Airport (GPT)plane FLO - GPT
8h 20m$106–476Fly to Jackson/Vicksburg
- Fly from Florence Regional Airport (FLO) to Jackson/Vicksburg (JAN)plane FLO - JAN
6h 36m$120–442
Florence to Mississippi by bus (Greyhound)
Questions & Answers
The cheapest way to get from Florence to Mississippi is to bus which costs $100 - $210 and takes 15h 20m.
The fastest way to get from Florence to Mississippi is to fly which takes 4h 48m and costs $150 - $700.
No, there is no direct bus from Florence station to Mississippi. However, there are services departing from Florence Bus Station and arriving at Jackson via Atlanta Bus Station. The journey, including transfers, takes approximately 15h 20m.
No, there is no direct train from Florence station to Mississippi. However, there are services departing from Florence Station and arriving at Jackson via Selma Station, Greensboro and New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 33h 8m.
The distance between Florence and Mississippi is 599 miles. The road distance is 675.2 miles.
The best way to get from Florence to Mississippi without a car is to bus which takes 15h 20m and costs $100 - $210.
It takes approximately 4h 48m to get from Florence to Mississippi, including transfers.
Florence to Mississippi bus services, operated by Greyhound USA, depart from Florence Bus Station.
Florence to Mississippi train services, operated by Amtrak, depart from Florence Station.
The best way to get from Florence to Mississippi is to fly which takes 4h 48m and costs $150 - $700. Alternatively, you can bus, which costs $100 - $210 and takes 15h 20m, you could also train, which costs $410 - $900 and takes 33h 8m.
What companies run services between Florence, SC, USA and Mississippi, USA?
American Airlines flies from Florence Regional Airport (FLO) to Memphis (MEM) once daily. Alternatively, you can take a bus from Florence Bus Station to Jackson via Atlanta Bus Station in around 15h 20m.
- Website
- aa.com
Flights from Florence Regional Airport to Memphis via Charlotte
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $120–650
Flights from Florence Regional Airport to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 10h 6m
- When
- Every day
- Estimated price
- $85–450
Flights from Florence Regional Airport to Jackson/Vicksburg via Charlotte
- Ave. Duration
- 9h
- When
- Every day
- Estimated price
- $70–380
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Florence Station to Selma Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- https://www.amtrak.com/home.html
Train from Selma Station to Greensboro
- Ave. Duration
- 2h 34m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to New Orleans Union Passenger Terminal
- Ave. Duration
- 21h 40m
- Frequency
- Once daily
- Estimated price
- $280–600
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Jackson
- Ave. Duration
- 3h 39m
- Frequency
- Once daily
- Estimated price
- $55–130
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Jackson
- Ave. Duration
- 7h 40m
- Frequency
- Twice daily
- Estimated price
- $55–120
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Florence to Mississippi bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Mississippi is 1h behind Florence. It is currently 6:54 AM in Florence and 5:54 AM in Mississippi.
Florence to Mississippi train services, operated by Amtrak, arrive at Selma Station.
Yes, the driving distance between Florence to Mississippi is 675 miles. It takes approximately 10h 58m to drive from Florence to Mississippi.
Book your Florence to Mississippi train tickets online with Omio.
Book your Florence to Mississippi bus tickets online with Omio and FlixBus.
There are 222+ hotels available in Mississippi.





