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How to get fromFlorence to Missoulaby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to Missoula

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There are 6 ways to get from Florence to Missoula by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Florence Regional Airport

    best
    1. Fly from Florence Regional Airport (FLO) to Missoula International Airport (MSO)plane plane FLO - MSO
    11h 8m
    $160–662

  2. Bus

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Minneapolis Bus Stationbus bus
    4. Take the bus from Minneapolis to Billingsbus bus
    5. Take the bus from Billings to Missoulabus bus
    2d 7h
    $481–806

  3. Bus, train

    1. Take the bus from Florence Bus Station to Raleigh Bus Stationbus bus
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Spokanetrain train
    4. Take the bus from Spokane to Missoulabus bus
    3d
    $1,015–2,171

  4. Drive 2,385.8 mi

    1. Drive from Florence to Missoulacar car 2,385.8 mi
    39h 48m
    $436–629

  5. Train to Charleston International Airport, fly

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Missoula International Airport (MSO)plane plane CHS - MSO
    12h 52m
    $195–717

  6. Bus, bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Missoula International Airport (MSO)plane plane CLT - MSO
    13h 27m
    $203–793

Florence to Missoula by bus

Calendar14Weekly Buses
Duration2d 7hAverage Duration
Ticket$481Cheapest Price
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Questions & Answers

Map of how to get from Florence to Missoula.ExpandLaunch map view
  • Distance: 1,994.6 mi
  • Duration: 11h 8m

What companies run services between Florence, SC, USA and Missoula, MT, USA?

American Airlines, United Airlines, and Delta fly from Florence Regional Airport (FLO) to Missoula International Airport (MSO) 4 times a day. Alternatively, you can take a bus from Florence Bus Station to Missoula via Atlanta Bus Station, Chicago Bus Station, Minneapolis, and Billings in around 2d 7h.

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