There are 8 ways to get from Florence to Mobile by bus (Greyhound), train (Amtrak), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Florence Bus Station to Atlanta Bus Stationbus Greyhound US0642 / ...
- Take the bus from Atlanta Bus Station to Mobile Bus Stationbus Greyhound US0602 / ...
15h 34m$131–215Fly Florence Regional Airport to Mobile Regional Airport
cheapest- Fly from Florence Regional Airport (FLO) to Mobile Regional Airport (MOB)plane FLO - MOB
10h 6m$80–382Train (Amtrak)
- Take the train from Florence Station to Selma Stationtrain
- Take the train from Selma Station to Greensborotrain
- Take the train from Greensboro to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain
32h 12m$388–851Drive 612.1 mi
- Drive from Florence to Mobilecar 612.1 mi
10h 2m$112–162Bus via Grand Bay
- Take the bus from Florence Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Grand Baybus
- Take the bus from Grand Bay to Mobilebus
15h 36m$164–248Bus via Sumter
- Take the bus from Florence to Sumterbus
- Take the bus from Sumter to Atlantabus
- Take the bus from Atlanta Bus Station to Mobile Bus Stationbus
15h 59m$151–227Fly Florence Regional Airport to Pensacola International Airport, bus
- Fly from Florence Regional Airport (FLO) to Pensacola International Airport (PNS)plane FLO - PNS
- Take the bus from Pensacola Airport to Mobile Bus Stationbus
8h 44m$80–361Bus to Myrtle Beach, fly to Mobile Regional Airport
- Take the bus from Florence to Myrtle Beachbus
- Fly from Myrtle Beach (MYR) to Mobile Regional Airport (MOB)plane MYR - MOB
9h 27m$111–407
Florence to Mobile by bus
Questions & Answers
The cheapest way to get from Florence to Mobile is to drive which costs $110 - $170 and takes 10h 2m.
The fastest way to get from Florence to Mobile is to fly and bus which takes 8h 44m and costs $80 - $370.
No, there is no direct bus from Florence station to Mobile. However, there are services departing from Florence Bus Station and arriving at Water NB at St Louis St via Atlanta Bus Station and Govt EB at Greyhound Bus Station. The journey, including transfers, takes approximately 15h 34m.
No, there is no direct train from Florence station to Mobile. However, there are services departing from Florence Station and arriving at Mobile Amtrak Sta via Selma Station, Greensboro and New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 32h 12m.
The distance between Florence and Mobile is 656 miles. The road distance is 615.7 miles.
The best way to get from Florence to Mobile without a car is to bus which takes 15h 34m and costs $130 - $220.
It takes approximately 15h 34m to get from Florence to Mobile, including transfers.
Florence to Mobile bus services, operated by Jefferson Lines, depart from Florence Bus Station.
Florence to Mobile train services, operated by Amtrak, depart from Florence Station.
The best way to get from Florence to Mobile is to bus which takes 15h 34m and costs $130 - $220. Alternatively, you can train, which costs $380 - $850 and takes 32h 12m, you could also fly, which costs $80 - $390 and takes 10h 6m.
What companies run services between Florence, SC, USA and Mobile, AL, USA?
You can take a bus from Florence Bus Station to Water NB at St Louis St via Atlanta Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 15h 34m. Alternatively, you can take a train from Florence Station to Mobile Amtrak Sta via Selma Station, Greensboro, and New Orleans Union Passenger Terminal in around 32h 12m.
- Website
- aa.com
Flights from Florence Regional Airport to Mobile Regional Airport via Charlotte
- Ave. Duration
- 9h 6m
- When
- Every day
- Estimated price
- $70–370
Flights from Florence Regional Airport to Pensacola International Airport via Charlotte
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $60–330
Flights from Myrtle Beach to Mobile Regional Airport via Charlotte
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $65–350
Flights from Myrtle Beach to Mobile Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 36m
- When
- Every day
- Estimated price
- $120–550
- Website
- delta.com
Flights from Myrtle Beach to Mobile Regional Airport via Atlanta
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $60–340
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Florence Station to Selma Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- https://www.amtrak.com/home.html
Train from Selma Station to Greensboro
- Ave. Duration
- 2h 34m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to New Orleans Union Passenger Terminal
- Ave. Duration
- 21h 40m
- Frequency
- Once daily
- Estimated price
- $280–600
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Mobile Amtrak Sta
- Ave. Duration
- 2h 43m
- Frequency
- Twice daily
- Estimated price
- $30–90
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 15m
- Frequency
- Twice daily
- Estimated price
- $75–110
- Book at
- https://www.jeffersonlines.com
- Adult
- $75–110
Bus from Atlanta Bus Station to Mobile Bus Station
- Ave. Duration
- 5h 45m
- Frequency
- 5 times a day
- Estimated price
- $80–120
- Book at
- https://www.jeffersonlines.com
- Adult
- $80–120
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 15m
- Frequency
- Twice daily
- Estimated price
- $75–110
- Book at
- https://www.jeffersonlines.com
- Adult
- $75–110
Bus from Florence to Sumter
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $21–29
- Book at
- https://www.jeffersonlines.com
- Adult
- $21–29
Bus from Sumter to Atlanta
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $65–95
- Book at
- https://www.jeffersonlines.com
- Adult
- $65–95
Bus from Atlanta Bus Station to Mobile Bus Station
- Ave. Duration
- 5h 45m
- Frequency
- 5 times a day
- Estimated price
- $80–120
- Book at
- https://www.jeffersonlines.com
- Adult
- $80–120
Bus from Florence to Myrtle Beach
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $27–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $27–40
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $50–95
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Mobile Bus Station
- Ave. Duration
- 5h 45m
- Frequency
- 5 times a day
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
Bus from Florence Bus Station to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $50–95
- Website
- https://www.greyhound.com/
Bus from Florence to Sumter
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $6–12
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Mobile Bus Station
- Ave. Duration
- 5h 45m
- Frequency
- 5 times a day
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
Bus from Pensacola Airport to Mobile Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $10–19
- Website
- https://www.greyhound.com/
- Phone
- +1 800-923-1799
- [email protected]
- Website
- omnibusexpress.com
Bus from Atlanta to Grand Bay
- Ave. Duration
- 5h 9m
- Frequency
- Once daily
- Estimated price
- $75–100
- Schedules at
- omnibusexpress.com
Bus from Grand Bay to Mobile
- Ave. Duration
- 24 min
- Frequency
- Once daily
- Estimated price
- $35–50
- Schedules at
- omnibusexpress.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Florence to Mobile bus services, operated by Jefferson Lines, arrive at Atlanta Bus Station.
Mobile is 1h behind Florence. It is currently 7:02 PM in Florence and 6:02 PM in Mobile.
Florence to Mobile train services, operated by Amtrak, arrive at Selma Station.
Yes, the driving distance between Florence to Mobile is 616 miles. It takes approximately 10h 2m to drive from Florence to Mobile.
Book your Florence to Mobile train tickets online with Omio.
Book your Florence to Mobile bus tickets online with Omio.
There are 202+ hotels available in Mobile.










