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How to get fromFlorence to Mobileby plane, bus (Greyhound), train (Amtrak), car, or bus

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There are 6 ways to get from Florence to Mobile by plane, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Florence Regional Airport

    best
    1. Fly from Florence Regional Airport (FLO) to Mobile Regional Airport (MOB)plane plane FLO - MOB
    5h 56m
    $105–442

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S / ...
    2. Take the bus from Atlanta Bus Station to Mobile Bus Stationbus bus Greyhound US0602 / ...
    14h 42m
    $97–158

  3. Train (Amtrak)

    1. Take the train from Florence Station to Selma Stationtrain train
    2. Take the train from Selma Station to Greensborotrain train
    3. Take the train from Greensboro to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    32h 12m
    $298–771

  4. Drive  612.1 mi

    1. Drive from Florence to Mobilecar car 612.1 mi
    10h 2m
    $112–162

  5. Bus to Myrtle Beach, fly

    1. Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus bus
    2. Fly from Myrtle Beach (MYR) to Mobile Regional Airport (MOB)plane plane MYR - MOB
    8h 11m
    $112–431

  6. Bus via Grand Bay

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Grand Baybus bus
    3. Take the bus from Grand Bay to Mobilebus bus
    15h 3m
    $160–226

Florence to Mobile by bus (Greyhound)

Calendar14Weekly Buses
Duration14h 42mAverage Duration
Ticket$97Cheapest Price
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Comparing Your Travel Options

Map of how to get from Florence to Mobile.ExpandLaunch map view
  • Distance: 568 mi
  • Duration: 5h 56m

What companies run services between Florence, SC, USA and Mobile, AL, USA?

American Airlines flies from Florence Regional Airport (FLO) to Mobile Regional Airport (MOB) 5 times a day. Alternatively, you can take a bus from Florence Bus Station to Govt Near Royal St via Atlanta Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 14h 42m.

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Want to know more about travelling around United States

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Need to know: Greyhound

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