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How to get fromFlorence to Naplesby plane, train, bus, bus (Flixbus), or car

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There are 7 ways to get from Florence to Naples by plane, train, bus, bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Florence Regional Airport to Ft. Myers

    best
    1. Fly from Florence Regional Airport (FLO) to Ft. Myers (RSW)plane plane FLO - RSW
    10h 59m
    $89–430

  2. Train, bus

    1. Take the train from Florence Station to Orlandotrain train
    2. Take the bus from Orlando to Fort Myers Amtrak Bus Stopbus bus
    3. Take the bus from Fort Myers 7-11 to Naples, FLbus bus
    18h 27m
    $268–474

  3. Bus (Flixbus)

    1. Take the bus from Florence to Orlando Bus Stationbus bus FlixBus N2472
    2. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    19h 26m
    $118–202

  4. Drive 632.4 mi

    1. Drive from Florence to Naplescar car 632.4 mi
    11h 5m
    $116–167

  5. Train to Charleston International Airport, fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    3. Take the bus from Fort Lauderdale Airport to Naples, FLbus bus
    8h 52m
    $251–1,243

  6. Train to Charleston International Airport, fly to Miami International Airport, bus

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane plane CHS - MIA
    3. Take the bus from Miami Airport to Naples, FLbus bus
    9h 21m
    $587–1,153

  7. Train, line 104 bus to Charleston International Airport, fly to Ft. Myers, line 240 bus, line 600 bus, line 11 bus

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from North Charleston Transit Center to Centre Pointe Dr / Tanger Outlet Blvdbus bus
    3. Fly from Charleston International Airport (CHS) to Ft. Myers (RSW)plane plane CHS - RSW
    4. Take the bus from South Fort Myers Transfer/P&R to Coconut Point Mallbus bus
    5. Take the bus from Coconut Point Mall to Creekside Way Transfer @ Immokalee Rdbus bus
    6. Take the bus from Creekside WLinC to 3rd Ave Sbus bus
    11h 49m

Florence Regional Airport (FLO) to Ft. Myers (RSW) flights

Calendar20Weekly Planes
Duration6h 40mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

Map of how to get from Florence to Naples.ExpandLaunch map view
  • Distance: 591.4 mi
  • Duration: 10h 59m

What companies run services between Florence, SC, USA and Naples, FL, USA?

American Airlines flies from Florence Regional Airport (FLO) to Ft. Myers (RSW) 3 times a day. Alternatively, you can take a vehicle from Florence to 3rd Ave S via Florence, Orlando Bus Station, Rosa Parks Transportation Ctr, South Fort Myers Transfer/P&R, Coconut Point Mall, Creekside Way Transfer @ Immokalee Rd, and Creekside WLinC in around 19h 26m.

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