There are 4 ways to get from Florence to Orlando by plane, train (Amtrak), bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Florence Regional Airport (FLO) to Orlando (MCO)plane FLO - MCO
4h 29m$77–364Bus
cheapest- Take the bus from Florence Bus Station to Sumter Bus Stopbus
- Take the bus from Sumter Bus Stop to Jacksonvillebus
- Take the bus from Jacksonville to Orlando Bus Stationbus
11h 55m$74–146Train (Amtrak)
- Take the train from Florence Station to Orlandotrain Silver Meteor
9h 46m$160–330Drive 446.8 mi
- Drive from Florence to Orlandocar 446.8 mi
7h 21m$82–118
Florence to Orlando by train (Amtrak)
Questions & Answers
The cheapest way to get from Florence to Orlando is to bus which costs $70 - $150 and takes 11h 55m.
The fastest way to get from Florence to Orlando is to fly which takes 4h 29m and costs $75 - $370.
No, there is no direct bus from Florence station to Orlando station. However, there are services departing from Florence Bus Station and arriving at Orlando Bus Station via Sumter Bus Stop and Jacksonville. The journey, including transfers, takes approximately 11h 55m.
Yes, there is a direct train departing from Florence Station station and arriving at Orlando. Services depart once daily, and operate every day. The journey takes approximately 9h 46m.
The distance between Florence and Orlando is 419 miles. The road distance is 449.4 miles.
The best way to get from Florence to Orlando without a car is to train which takes 9h 46m and costs $160 - $330.
It takes approximately 4h 29m to get from Florence to Orlando, including transfers.
Florence to Orlando bus services, operated by Greyhound USA, depart from Florence Bus Station.
Florence to Orlando train services, operated by Amtrak, depart from Florence Station.
The best way to get from Florence to Orlando is to fly which takes 4h 29m and costs $75 - $370. Alternatively, you can train, which costs $160 - $330 and takes 9h 46m, you could also bus, which costs $70 - $150 and takes 11h 55m.
What companies run services between Florence, SC, USA and Orlando, FL, USA?
American Airlines flies from Florence Regional Airport (FLO) to Orlando (MCO) once daily. Alternatively, Amtrak operates a train from Florence Station to Orlando once daily. Tickets cost $160–330 and the journey takes 9h 46m.
- Website
- aa.com
Flights from Florence Regional Airport to Orlando via Charlotte
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $65–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Florence Station to Orlando
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $160–330
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Florence Bus Station to Sumter Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $6–12
- Website
- https://www.greyhound.com/
Bus from Sumter Bus Stop to Jacksonville
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Jacksonville to Orlando Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a day
- Estimated price
- $23–40
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Florence to Orlando bus services, operated by Greyhound USA, arrive at Sumter Bus Stop station.
Florence to Orlando train services, operated by Amtrak, arrive at Orlando station.
Yes, the driving distance between Florence to Orlando is 449 miles. It takes approximately 7h 21m to drive from Florence to Orlando.
Book your Florence to Orlando train tickets online with Omio.
Book your Florence to Orlando bus tickets online with Omio and FlixBus.
There are 1870+ hotels available in Orlando.






