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How to get fromFlorence to Pennsylvaniaby train (Amtrak), bus (Greyhound), car, bus, plane, bus (Greyhound, Flixbus), or train

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There are 10 ways to get from Florence to Pennsylvania by train (Amtrak), bus (Greyhound), car, bus, plane, bus (Greyhound, Flixbus), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Florence Station to 30th Street Stationtrain train Palmetto / ...
    11h 2m
    $178–360

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Florence Bus Station to Raleigh Bus Stationbus bus Greyhound US0642S / ...
    2. Take the bus from Raleigh Bus Station to Philadelphia Bus Stationbus bus Greyhound US0670
    13h 30m
    $83–164

  3. Drive 533.7 mi

    1. Drive from Florence to Philadelphiacar car 533.7 mi
    9h 24m
    $98–141

  4. Bus, bus to Charlotte Douglas International Airport, fly to Philadelphia International Airport

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Philadelphia International Airport (PHL)plane plane CLT - PHL
    7h 57m
    $135–236

  5. Bus via Washington

    1. Take the bus from Florence Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Philadelphia Bus Stationbus bus
    13h 30m
    $83–155

  6. Bus, bus to Charlotte Douglas International Airport, fly to Pittsburgh International Airport

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Pittsburgh International Airport (PIT)plane plane CLT - PIT
    8h 24m
    $97–503

  7. Bus, bus to Columbia, fly to Philadelphia International Airport

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Columbia, SCbus bus
    3. Fly from Columbia (CAE) to Philadelphia International Airport (PHL)plane plane CAE - PHL
    8h 38m
    $242–1,161

  8. Train, bus to Myrtle Beach, fly to Philadelphia International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Philadelphia International Airport (PHL)plane plane MYR - PHL
    8h 23m
    $130–528

  9. Train, bus to Myrtle Beach, fly to Pittsburgh International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Pittsburgh International Airport (PIT)plane plane MYR - PIT
    8h 53m
    $227–905

  10. Train, bus to Myrtle Beach, fly to Lehigh Valley International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Lehigh Valley International Airport (ABE)plane plane MYR - ABE
    8h 27m
    $114–427

Florence to Pennsylvania by train and tram (Amtrak)

Calendar14Weekly Services
Duration11h 2mAverage Duration
Ticket$178Cheapest Price
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Questions & Answers

Map of how to get from Florence to Pennsylvania.ExpandLaunch map view
  • Distance: 542.7 mi
  • Duration: 11h 2m

What companies run services between Florence, SC, USA and Pennsylvania, USA?

Amtrak operates a train from Florence Station to 30th Street Station twice daily. Tickets cost $170–360 and the journey takes 10h 57m. Alternatively, you can take a bus from Florence Bus Station to Philadelphia Bus Station via Raleigh Bus Station in around 13h 30m.

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