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How to get fromFlorence to Philadelphiaby train (Amtrak), bus (Greyhound, Flixbus), car, train, plane, bus (Greyhound), or bus

Find Transport to Philadelphia

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There are 9 ways to get from Florence to Philadelphia by train (Amtrak), bus (Greyhound, Flixbus), car, train, plane, bus (Greyhound), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Florence Station to 30th Street Stationtrain train Palmetto / ...
    10h 57m
    $140–310

  2. Bus via Washington

    cheapest
    1. Take the bus from Florence Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Philadelphia Bus Stationbus bus
    13h 30m
    $79–131

  3. Drive  533.8 mi

    1. Drive from Florence to Philadelphiacar car 533.8 mi
    9h 24m
    $98–141

  4. Train to Charleston International Airport, fly

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Philadelphia International Airport (PHL)plane plane CHS - PHL
    7h 6m
    $680–962

  5. Bus (Greyhound)

    1. Take the bus from Florence Bus Station to Raleigh Bus Stationbus bus Greyhound US0642S / ...
    2. Take the bus from Raleigh Bus Station to Philadelphia Bus Stationbus bus Greyhound US0670
    13h 35m
    $84–137

  6. Bus, bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Philadelphia International Airport (PHL)plane plane CLT - PHL
    8h 5m
    $135–229

  7. Train, bus to Wilmington International Airport, fly

    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train
    2. Take the bus from Fayetteville Bus Station to Wilmington Cape Fear Public Transitbus bus
    3. Fly from Wilmington International Airport (ILM) to Philadelphia International Airport (PHL)plane plane ILM - PHL
    8h 17m
    $120–498

  8. Bus, bus to Columbia, fly

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Columbia, SCbus bus
    3. Fly from Columbia (CAE) to Philadelphia International Airport (PHL)plane plane CAE - PHL
    8h 36m
    $117–490

  9. Train, bus to Myrtle Beach, fly

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Philadelphia International Airport (PHL)plane plane MYR - PHL
    8h 21m
    $117–747

Florence to Philadelphia by train (Amtrak)

Calendar14Weekly Trains
Duration10h 57mAverage Duration
Ticket$140Cheapest Price
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Comparing Your Travel Options

Map of how to get from Florence to Philadelphia.ExpandLaunch map view
  • Distance: 541.5 mi
  • Duration: 10h 57m

What companies run services between Florence, SC, USA and Philadelphia, PA, USA?

Amtrak operates a train from Florence Station to 30th Street Station twice daily. Tickets cost $140–310 and the journey takes 10h 57m. Alternatively, you can take a bus from Florence Bus Station to Philadelphia Bus Station via Fayetteville Bus Station and Washington Union Station in around 13h 30m.

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Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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