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How to get fromFlorence to Philadelphiaby bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Greyhound)

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There are 8 ways to get from Florence to Philadelphia by bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Myrtle Beach, fly to Philadelphia International Airport

    best
    1. Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus bus
    2. Fly from Myrtle Beach (MYR) to Philadelphia International Airport (PHL)plane plane MYR - PHL
    5h 22m
    $90–686

  2. Bus via Washington

    cheapest
    1. Take the bus from Florence Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Philadelphia Bus Stationbus bus
    13h 5m
    $87–138

  3. Train (Amtrak)

    1. Take the train from Florence Station to 30th Street Stationtrain train Palmetto / ...
    10h 57m
    $300–460

  4. Drive  533.8 mi

    1. Drive from Florence to Philadelphiacar car 533.8 mi
    9h 24m
    $98–141

  5. Bus to Myrtle Beach, fly to Baltimore-Washington International Airport, train

    1. Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus bus
    2. Fly from Myrtle Beach (MYR) to Baltimore-Washington International Airport (BWI)plane plane MYR - BWI
    3. Take the train from BWI Thurgood Marshall to 30th Street Stationtrain train
    6h 25m
    $347–1,334

  6. Train to Charleston International Airport, fly to Philadelphia International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Philadelphia International Airport (PHL)plane plane CHS - PHL
    7h 6m
    $709–989

  7. Bus, bus to Charlotte Douglas International Airport, fly to Philadelphia International Airport

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Philadelphia International Airport (PHL)plane plane CLT - PHL
    7h 50m
    $139–244

  8. Bus (Greyhound)

    1. Take the bus from Florence Bus Station to Raleigh Bus Stationbus bus Greyhound US0642S / ...
    2. Take the bus from Raleigh Bus Station to Philadelphia Bus Stationbus bus Greyhound US0670
    13h 35m
    $97–150

Florence to Philadelphia by train (Amtrak)

Calendar14Weekly Trains
Duration10h 57mAverage Duration
Ticket$300Cheapest Price
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Comparing Your Travel Options

Map of how to get from Florence to Philadelphia.ExpandLaunch map view
  • Distance: 552.9 mi
  • Duration: 5h 22m

What companies run services between Florence, SC, USA and Philadelphia, PA, USA?

Amtrak operates a train from Florence Station to 30th Street Station twice daily. Tickets cost $300–460 and the journey takes 10h 57m. Alternatively, you can take a bus from Florence Bus Station to Philadelphia Bus Station via Fayetteville Bus Station and Washington Union Station in around 13h 5m.

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