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How to get fromFlorence to Poughkeepsieby train (Amtrak), bus, car, plane, or train

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There are 10 ways to get from Florence to Poughkeepsie by train (Amtrak), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Florence Station to Ny Moynihan Train Hall At Penn Stationtrain train Palmetto / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Stationtrain train Empire Service / ...
    14h 49m
    $181–404

  2. Bus

    cheapest
    1. Take the bus from Florence, SC to New York, NYbus bus Florence
    2. Take the bus from TransCenter to Metro North Stationbus bus Wpp
    17h 29m
    $96–139

  3. Drive  691.7 mi

    1. Drive from Florence to Poughkeepsiecar car 691.7 mi
    12h 28m
    $127–183

  4. Bus, bus to Charlotte Douglas International Airport, fly to Laguardia Airport, train

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Laguardia Airport (LGA)plane plane CLT - LGA
    4. Take the train from 125th Street - Harlem to Poughkeepsietrain train
    10h 18m
    $174–671

  5. Bus, train

    1. Take the bus from Florence Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to New York City Chinatownbus bus
    3. Take the train from 125th Street - Harlem to Poughkeepsietrain train
    17h 36m
    $120–197

  6. Train, bus to Wilmington International Airport, fly to Laguardia Airport

    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train
    2. Take the bus from Fayetteville Bus Station to Wilmington Cape Fear Public Transitbus bus
    3. Fly from Wilmington International Airport (ILM) to Laguardia Airport (LGA)plane plane ILM - LGA
    4. Take the train from 125th Street - Harlem to Poughkeepsietrain train
    10h 25m
    $159–620

  7. Train, bus to Myrtle Beach, fly to Laguardia Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Laguardia Airport (LGA)plane plane MYR - LGA
    4. Take the train from 125th Street - Harlem to Poughkeepsietrain train
    10h 28m
    $156–609

  8. Train, bus to Myrtle Beach, fly to Newark Liberty International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Newark Liberty International Airport (EWR)plane plane MYR - EWR
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Stationtrain train
    10h 50m
    $439–866

  9. Train, bus to Myrtle Beach, fly to Stewart International Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Stewart International Airport (SWF)plane plane MYR - SWF
    10h 10m
    $118–463

  10. Train, bus to Myrtle Beach, fly to Westchester County Airport

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Westchester County Airport (HPN)plane plane MYR - HPN
    4. Take the train from 125th Street - Harlem to Poughkeepsietrain train
    12h 30m
    $154–568

Florence to Poughkeepsie by train (Amtrak)

Calendar14Weekly Trains
Duration14h 49mAverage Duration
Ticket$181Cheapest Price
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Comparing Your Travel Options

Map of how to get from Florence to Poughkeepsie.ExpandLaunch map view
  • Distance: 704.4 mi
  • Duration: 14h 49m

What companies run services between Florence, SC, USA and Poughkeepsie, NY, USA?

You can take a train from Florence Station to Poughkeepsie Amtrak Station via Ny Moynihan Train Hall At Penn Station in around 14h 49m. Alternatively, you can take a bus from Florence, SC to Metro North Station via New York, NY, Delancey St-Essex St, 23 St, New York Midtown, White Plains Station, and TransCenter in around 17h 29m.

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