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How to get fromFlorence to Roanokeby plane, train, bus, bus (Greyhound, Flixbus), car, or train (Amtrak)

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There are 5 ways to get from Florence to Roanoke by plane, train, bus, bus (Greyhound, Flixbus), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Florence Regional Airport (FLO) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane FLO - ROA
    4h 32m
    $59–317

  2. Drive 240.9 mi

    cheapest
    1. Drive from Florence to Roanokecar car 240.9 mi
    4h 54m
    $44–64

  3. Train, bus

    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train
    2. Take the bus from Fayetteville to High Point Terminalbus bus
    3. Take the train from High Point to Lynchburgtrain train
    4. Take the train from Lynchburg to Roanoketrain train
    10h 49m
    $99–210

  4. Bus

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Lynchburg Transit Centerbus bus
    4. Take the bus from Lynchburg Transit Center to Roanoke Bus Stopbus bus
    12h 4m
    $61–122

  5. Train (Amtrak)

    1. Take the train from Florence Station to Selma Stationtrain train
    2. Take the train from Selma Station to Greensborotrain train
    3. Take the train from Greensboro to Lynchburgtrain train
    4. Take the train from Lynchburg to Roanoketrain train
    11h 13m
    $129–272

Florence to Roanoke by train and bus

Calendar7Weekly Services
Duration10h 49mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Florence to Roanoke.ExpandLaunch map view
  • Distance: 226 mi
  • Duration: 4h 32m

What companies run services between Florence, SC, USA and Roanoke, VA, USA?

American Airlines flies from Florence Regional Airport (FLO) to Roanoke Regional Airport-Woodrum Field (ROA) 6 times a week. Alternatively, you can take a bus from Florence Bus Station to Roanoke Bus Stop via Camden, Charlotte Bus Station, and Lynchburg Transit Center in around 12h 4m.

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