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How to get fromFlorence to Rochesterby plane, bus, train (Amtrak), car, or bus (Greyhound, Flixbus)

Find Transport to Rochester

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There are 7 ways to get from Florence to Rochester by plane, bus, train (Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Florence Regional Airport

    best
    1. Fly from Florence Regional Airport (FLO) to Rochester (ROC)plane plane FLO - ROC
    6h 14m
    $165–831

  2. Drive  752.6 mi

    cheapest
    1. Drive from Florence to Rochestercar car 752.6 mi
    14h
    $133–193

  3. Bus

    1. Take the bus from Florence, SC to New York, NYbus bus Florence
    2. Take the bus from New York to Rochesterbus bus Adt N816-D / ...
    19h 49m
    $142–354

  4. Train (Amtrak)

    1. Take the train from Florence Station to Ny Moynihan Train Hall At Penn Stationtrain train Palmetto / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Rochestertrain train Empire Service / ...
    20h 24m
    $549–855

  5. Bus to Myrtle Beach, fly

    1. Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus bus
    2. Fly from Myrtle Beach (MYR) to Rochester (ROC)plane plane MYR - ROC
    4h 59m
    $169–801

  6. Bus via Fayetteville

    1. Take the bus from Florence Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Rochester Bus Stopbus bus
    19h 55m
    $151–244

  7. Train via New York

    1. Take the train from Florence Station to Ny Moynihan Train Hall At Penn Stationtrain train Palmetto / ...
    2. Take the train from New York Penn Station to Rochestertrain train VIA Rail
    20h 24m
    $444–795

Florence to Rochester by train (Amtrak)

Calendar14Weekly Trains
Duration20h 24mAverage Duration
Ticket$549Cheapest Price
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Comparing Your Travel Options

Map of how to get from Florence to Rochester.ExpandLaunch map view
  • Distance: 633.4 mi
  • Duration: 6h 14m

What companies run services between Florence, SC, USA and Rochester, NY, USA?

American Airlines flies from Florence Regional Airport (FLO) to Rochester (ROC) 3 times a day. Alternatively, you can take a bus from Florence, SC to Rochester via New York, NY, Canal St, 42 St-Times Square, and New York in around 19h 49m.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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