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How to get fromFlorence to San Diegoby plane, bus (Greyhound, Amtrak), train (Amtrak), car, or train

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There are 5 ways to get from Florence to San Diego by plane, bus (Greyhound, Amtrak), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Florence Regional Airport

    best
    1. Fly from Florence Regional Airport (FLO) to San Diego International Airport (SAN)plane plane FLO - SAN
    7h 10m
    $190–762

  2. Bus

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to San Diegobus bus
    2d 12h
    $415–805

  3. Train (Amtrak)

    1. Take the train from Florence Station to Selma Stationtrain train
    2. Take the train from Selma Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    5. Take the train from Fullerton Amtrak Station to San Diegotrain train
    3d 4h
    $1,121–2,425

  4. Drive 2,430 mi

    1. Drive from Florence to San Diegocar car 2,430 mi
    38h 4m
    $444–641

  5. Train to Fayetteville Municipal Airport, fly

    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train
    2. Fly from Fayetteville Municipal Airport (FAY) to San Diego International Airport (SAN)plane plane FAY - SAN
    9h 29m
    $223–825

Florence to San Diego by bus and foot

Calendar7Weekly Services
Duration2d 12hAverage Duration
Ticket$415Cheapest Price
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Questions & Answers

Map of how to get from Florence to San Diego.ExpandLaunch map view
  • Distance: 2,152.2 mi
  • Duration: 7h 10m

What companies run services between Florence, SC, USA and San Diego, CA, USA?

American Airlines flies from Florence Regional Airport (FLO) to San Diego International Airport (SAN) 3 times a day. Alternatively, you can take a bus from Florence Bus Station to San Diego via Atlanta Bus Station, Dallas Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 12h.

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Want to know more about travelling around United States

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