Rome2Rio

How to get fromFlorence to San Franciscoby plane, bus (Greyhound), bus, train, or car

Find Transport to San Francisco

See all options

There are 4 ways to get from Florence to San Francisco by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Florence Regional Airport (FLO) to San Francisco International Airport (SFO)plane plane FLO - SFO
    8h 14m
    $149–574
  2. Bus (Greyhound)

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles Union Station to San Francisco Bus Stationbus bus
    2d 17h
    $435–865
  3. Bus, train

    1. Take the bus from Florence Bus Station to Raleigh Bus Stationbus bus
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Richmondtrain train
    3d 12h
    $1,119–2,402
  4. Drive 2,751.6 mi

    1. Drive from Florence to San Franciscocar car 2,751.6 mi
    43h 48m
    $503–726

Florence to San Francisco by bus (Greyhound)

Calendar20Weekly Buses
Duration2d 17hAverage Duration
Ticket$435Cheapest Price
See schedules

Questions & Answers

What companies run services between Florence, SC, USA and San Francisco, CA, USA?

American Airlines flies from Florence Regional Airport (FLO) to San Francisco International Airport (SFO) 4 times a day. Alternatively, you can take a bus from Florence Bus Station to San Francisco Bus Station via Atlanta Bus Station, Dallas Bus Station, and Los Angeles Union Station in around 2d 17h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers