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How to get fromFlorence to Senecaby bus, taxi, train, car, plane, or train (Amtrak)

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There are 6 ways to get from Florence to Seneca by bus, taxi, train, car, plane, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    4. Take the taxi from Taqueria Guadalajara - Greenville to Senecataxi taxi
    8h 36m
    $160–303

  2. Drive 209.1 mi

    cheapest
    1. Drive from Florence to Senecacar car 209.1 mi
    3h 50m
    $39–56

  3. Bus, train

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train
    8h 37m
    $84–168

  4. Fly to Greenville–Spartanburg International Airport, taxi

    1. Fly from Florence Regional Airport (FLO) to Greenville–Spartanburg International Airport (GSP)plane plane FLO - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    5h 10m
    $195–592

  5. Train (Amtrak)

    1. Take the train from Florence Station to Selma Stationtrain train
    2. Take the train from Selma Station to Charlotte Amtrak Stationtrain train
    3. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train
    11h 57m
    $171–351

  6. Fly to Asheville Regional Airport, drive

    1. Fly from Florence Regional Airport (FLO) to Asheville Regional Airport (AVL)plane plane FLO - AVL
    2. Drive from Asheville-Airport-AVL to Senecacar car
    5h 21m
    $62–311

Florence Regional Airport (FLO) to Greenville–Spartanburg International Airport (GSP) flights

Calendar13Weekly Planes
Duration4h 28mAverage Duration
Ticket$58Cheapest Price
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Questions & Answers

Map of how to get from Florence to Seneca.ExpandLaunch map view
  • Distance: 278.2 mi
  • Duration: 8h 36m

What companies run services between Florence, SC, USA and Seneca, SC, USA?

You can take a train from Florence Station to Seneca via Selma Station, Charlotte Amtrak Station, and Clemson Amtrak Station in around 11h 57m.

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