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How to get fromFlorence to Siesta Keyby plane, bus (Flixbus), train, bus, or car

Find Transport to Siesta Key

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There are 5 ways to get from Florence to Siesta Key by plane, bus (Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Florence Regional Airport (FLO) to Sarasota–Bradenton International Airport (SRQ)plane plane FLO - SRQ
    7h
    $107–566

  2. Drive 552 mi

    cheapest
    1. Drive from Florence to Siesta Keycar car 552 mi
    9h 33m
    $101–146

  3. Bus

    1. Take the bus from Florence Bus Station to Orlando Bus Stationbus bus FlixBus 2433
    2. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus bus FlixBus 2421
    15h 6m
    $132–188

  4. Train, Amtrak Thruway (Amtrak)

    1. Take the train from Florence Station to Orlandotrain train Silver Meteor
    2. Take the bus from Orlando, FL to Sarasota Amtrak Bus Stopbus bus Amtrak Thruway Connecting Service
    16h 43m
    $214–401

  5. Train, bus

    1. Take the train from Florence Station to Kissimmee Amtrak Stationtrain train
    2. Take the train from Kissimmee Amtrak Station to Tampatrain train
    3. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    17h 6m
    $204–403

Florence to Siesta Key by bus

Calendar7Weekly Buses
Duration15h 6mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Florence to Siesta Key.ExpandLaunch map view
  • Distance: 516.1 mi
  • Duration: 7h

What companies run services between Florence, SC, USA and Siesta Key, FL, USA?

American Airlines flies from Florence Regional Airport (FLO) to Sarasota–Bradenton International Airport (SRQ) twice daily. Alternatively, you can take a bus from Florence Bus Station to Ocean Blvd @ Avenida Madera via Orlando Bus Station, Sarasota Cattlemen Transfer Center, and Cattlemen Transit Station in around 15h 6m.

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