Rome2Rio

How to get fromFlorence to Sioux Fallsby train, plane, bus (Greyhound, Flixbus), bus, or car

Find Transport to Sioux Falls

See all options

There are 10 ways to get from Florence to Sioux Falls by train, plane, bus (Greyhound, Flixbus), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Fayetteville Municipal Airport, fly

    best
    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train
    2. Fly from Fayetteville Municipal Airport (FAY) to Sioux Falls (FSD)plane plane FAY - FSD
    9h 11m
    $156–577

  2. Bus, bus to Charlotte Douglas International Airport, fly

    cheapest
    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Sioux Falls (FSD)plane plane CLT - FSD
    11h 41m
    $144–645

  3. Bus via Kansas City

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    4. Take the bus from Kansas City to Sioux Fallsbus bus
    35h 33m
    $262–473

  4. Train, bus

    1. Take the train from Florence Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Albert Leabus bus
    5. Take the bus from Albert Lea to Sioux Fallsbus bus
    43h 18m
    $595–1,185

  5. Drive 1,397.4 mi

    1. Drive from Florence to Sioux Fallscar car 1,397.4 mi
    24h 28m
    $255–369

  6. Train to Charleston International Airport, fly

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Fly from Charleston International Airport (CHS) to Sioux Falls (FSD)plane plane CHS - FSD
    11h 14m
    $147–558

  7. Bus, bus to Columbia, fly

    1. Take the bus from Florence Bus Station to Camdenbus bus
    2. Take the bus from Camden to Columbia, SCbus bus
    3. Fly from Columbia (CAE) to Sioux Falls (FSD)plane plane CAE - FSD
    12h 22m
    $281–1,160

  8. Train, bus to Myrtle Beach, fly

    1. Take the train from Florence Station to Charleston Amtrak Stationtrain train
    2. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Sioux Falls (FSD)plane plane MYR - FSD
    13h 1m
    $159–557

  9. Bus

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Saint Cloudbus bus
    4. Take the bus from St. Cloud to Sioux Fallsbus bus
    43h 18m
    $297–523

  10. Train, bus via Kansas City

    1. Take the train from Florence Station to Selma Stationtrain train
    2. Take the train from Selma Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Kansas Citytrain train
    5. Take the bus from Kansas City to Sioux Fallsbus bus
    2d 1h
    $636–1,298

Fayetteville Municipal Airport (FAY) to Sioux Falls (FSD) flights

Calendar14Weekly Planes
Duration8h 1mAverage Duration
Ticket$115Cheapest Price
See schedules

Questions & Answers

Map of how to get from Florence to Sioux Falls.ExpandLaunch map view
  • Distance: 1,214.2 mi
  • Duration: 9h 11m

What companies run services between Florence, SC, USA and Sioux Falls, SD, USA?

You can take a bus from Florence Bus Station to The Bus Stop via Atlanta Bus Station, St Louis Bus Station, Kansas City Bus Station, Kansas City, Sioux Falls, and Maple/Career NE corner in around 35h 33m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers