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How to get fromFlorence to Tallahasseeby plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

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There are 6 ways to get from Florence to Tallahassee by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Florence Regional Airport

    best
    1. Fly from Florence Regional Airport (FLO) to Tallahassee (TLH)plane plane FLO - TLH
    4h 15m
    $107–479

  2. Drive 407.4 mi

    cheapest
    1. Drive from Florence to Tallahasseecar car 407.4 mi
    7h 52m
    $75–108

  3. Bus

    1. Take the bus from Florence to Jacksonvillebus bus FlixBus N2472
    2. Take the bus from Jacksonville to Tallahasseebus bus Greyhound US0760S
    10h 1m
    $89–153

  4. Train, bus

    1. Take the train from Florence Station to Jacksonvilletrain train Silver Meteor
    2. Take the bus from Jacksonville to Tallahasseebus bus Greyhound US0760S
    11h 10m
    $135–278

  5. Train to Fayetteville Municipal Airport, fly

    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train
    2. Fly from Fayetteville Municipal Airport (FAY) to Tallahassee (TLH)plane plane FAY - TLH
    6h 18m
    $140–542

  6. Bus via Sumter (Greyhound)

    1. Take the bus from Florence Bus Station to Sumter Bus Stopbus bus
    2. Take the bus from Sumter Bus Stop to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Tallahasseebus bus
    12h 30m
    $75–151

Florence to Tallahassee by train and bus

Calendar7Weekly Services
Duration11h 10mAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

Map of how to get from Florence to Tallahassee.ExpandLaunch map view
  • Distance: 384.4 mi
  • Duration: 4h 15m

What companies run services between Florence, SC, USA and Tallahassee, FL, USA?

American Airlines flies from Florence Regional Airport (FLO) to Tallahassee (TLH) twice daily. Alternatively, you can take a vehicle from Florence to Tallahassee via Florence and Jacksonville in around 10h 1m.

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