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How to get fromFlorence to Winston-Salemby train, bus, car, plane, or bus (Greyhound)

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There are 6 ways to get from Florence to Winston-Salem by train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Fayetteville

    best
    1. Take the train from Florence Station to Fayetteville Amtrak Stationtrain train Palmetto / ...
    2. Take the bus from Fayetteville to Winston-Salembus bus Winston-Salem to Fayetteville
    5h 51m
    $48–99

  2. Drive 159.2 mi

    cheapest
    1. Drive from Florence to Winston-Salemcar car 159.2 mi
    3h 5m
    $30–42

  3. Train, bus

    1. Take the train from Florence Station to Selma Stationtrain train
    2. Take the train from Selma Station to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    7h 19m
    $81–169

  4. Fly to Piedmont Triad International Airport

    1. Fly from Florence Regional Airport (FLO) to Piedmont Triad International Airport (GSO)plane plane FLO - GSO
    4h 35m
    $94–495

  5. Bus

    1. Take the bus from Florence Bus Station to Fayetteville Bus Stationbus bus Greyhound US0642S / ...
    2. Take the bus from Fayetteville to Winston-Salembus bus Winston-Salem to Fayetteville
    6h 20m
    $35–70

  6. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Florence Regional Airport (FLO) to Charlotte Douglas International Airport (CLT)plane plane FLO - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    4h 34m
    $71–448

Florence to Winston-Salem by train and bus

Calendar14Weekly Services
Duration5h 51mAverage Duration
Ticket$48Cheapest Price
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Questions & Answers

Map of how to get from Florence to Winston-Salem.ExpandLaunch map view
  • Distance: 230.4 mi
  • Duration: 5h 51m

What companies run services between Florence, SC, USA and Winston-Salem, NC, USA?

American Airlines flies from Florence Regional Airport (FLO) to Piedmont Triad International Airport (GSO) 4 times a day. Alternatively, you can take a bus from Florence Bus Station to Winston-Salem via Fayetteville Bus Station and Fayetteville in around 6h 20m.

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