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How to get fromFlorence, SC to Saint Louis Countyby plane, bus (Greyhound, Flixbus), or car

Find Transport to Saint Louis County

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There are 4 ways to get from Florence, SC to Saint Louis County by plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Florence Regional Airport

    best
    1. Fly from Florence Regional Airport (FLO) to Lambert–St. Louis International Airport (STL)plane plane FLO - STL
    6h
    $123–576
  2. Drive to Myrtle Beach, fly

    cheapest
    1. Drive from Florence, SC to Myrtle Beach (MYR)car car
    2. Fly from Myrtle Beach (MYR) to Lambert–St. Louis International Airport (STL)plane plane MYR - STL
    5h 8m
    $112–522
  3. Bus

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    21h 5m
    $148–275
  4. Drive 832.6 mi

    1. Drive from Florence, SC to Saint Louis Countycar car 832.6 mi
    13h 59m
    $152–220

Florence Regional Airport (FLO) to Lambert–St. Louis International Airport (STL) flights

Calendar6Weekly Planes
Duration4h 54mAverage Duration
Ticket$104Cheapest Price
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Questions & Answers

What companies run services between Florence, SC, USA and Saint Louis County, MO, USA?

American Airlines flies from Florence Regional Airport (FLO) to Lambert–St. Louis International Airport (STL) 6 times a week. Alternatively, you can take a vehicle from Florence, SC to Clayton @ Ballas Wb via Florence Bus Station, Atlanta Bus Station, St Louis Bus Station, CIVIC CENTER station, CLAYTON station, and Clayton Transit Center in around 21h 5m.

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