There are 6 ways to get from Florence Station to Wytheville by bus (Greyhound), train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Florence Bus Station to Camdenbus
- Take the bus from Camden to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Max Meadowsbus
7h 19m$72–122Drive 240.6 mi
cheapest- Drive from Florence Station to Wythevillecar 240.6 mi
4h 41m$44–64Train, bus
- Take the train from Florence Station to Selma Stationtrain
- Take the train from Selma Station to Greensborotrain
- Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Wythevillebus
9h 48m$104–231Fly, bus
- Fly from Florence Regional Airport (FLO) to Charlotte Douglas International Airport (CLT)plane FLO - CLT
- Take the bus from Charlotte Bus Station to Max Meadowsbus
5h 24m$118–493Bus via Wytheville
- Take the bus from Florence Bus Station to Camdenbus
- Take the bus from Camden to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Wythevillebus
7h 59m$56–120Train, bus via Fayetteville
- Take the train from Florence Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville to Winston-Salembus
- Take the bus from Winston Salem(Trans Center) to Wythevillebus
8h 20m$77–166
Florence Regional Airport (FLO) to Charlotte Douglas International Airport (CLT) flights
Questions & Answers
The cheapest way to get from Florence Station to Wytheville is to drive which costs $40 - $65 and takes 4h 41m.
The fastest way to get from Florence Station to Wytheville is to drive which takes 4h 41m and costs $40 - $65.
No, there is no direct bus from Florence Station station to Wytheville. However, there are services departing from Florence Bus Station and arriving at Max Meadows via Camden and Charlotte Bus Station. The journey, including transfers, takes approximately 7h 19m.
The distance between Florence Station and Wytheville is 277 miles. The road distance is 242 miles.
The best way to get from Florence Station to Wytheville without a car is to bus which takes 7h 19m and costs $70 - $130.
It takes approximately 7h 19m to get from Florence Station to Wytheville, including transfers.
Florence Station to Wytheville bus services, operated by Greyhound USA, depart from Florence Bus Station.
Florence Station to Wytheville bus services, operated by Greyhound USA, arrive at Camden station.
Yes, the driving distance between Florence Station to Wytheville is 242 miles. It takes approximately 4h 41m to drive from Florence Station to Wytheville.
There are 35+ hotels available in Wytheville.
What companies run services between Florence Station, SC, USA and Wytheville, VA, USA?
You can take a vehicle from Florence Station to Wytheville via Florence Bus Station, Camden, Charlotte Bus Station, and Max Meadows in around 7h 19m.
- Website
- aa.com
Flights from Florence Regional Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $50–390
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Florence Station to Selma Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- Amtrak
Train from Selma Station to Greensboro
- Ave. Duration
- 2h 34m
- Frequency
- Once daily
- Estimated price
- $30–70
- Website
- Amtrak
Train from Florence Station to Fayetteville Amtrak Station
- Ave. Duration
- 1h 21m
- Frequency
- Twice daily
- Estimated price
- $25–55
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Florence Bus Station to Camden
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $7–14
- Website
- Greyhound
Bus from Camden to Charlotte Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $11–23
- Website
- Greyhound
Bus from Charlotte Bus Station to Max Meadows
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $19–40
- Website
- Greyhound
Bus from Greensboro Bus Stop to Winston Salem(Trans Center)
- Ave. Duration
- 30 min
- Frequency
- 4 times a day
- Estimated price
- $4–8
- Website
- Greyhound
Bus from Charlotte Bus Station to Max Meadows
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $19–40
- Website
- Greyhound
Bus from Florence Bus Station to Camden
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $7–14
- Website
- Greyhound
Bus from Camden to Charlotte Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $11–23
- Website
- Greyhound
Bus from Fayetteville to Winston-Salem
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $22–45
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Winston Salem(Trans Center) to Wytheville
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- Barons Bus
Bus from Charlotte Bus Station to Wytheville
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- $15–55
- Website
- Barons Bus
Bus from Winston Salem(Trans Center) to Wytheville
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- Barons Bus
- Phone
- +1 704-348-1200
- [email protected]
- Website
- sunwaycharters.com
Bus from Fayetteville to Winston-Salem
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $23–35
- Schedules at
- sunwaycharters.com
- Passenger
- $23–35
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide









