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How to get fromFlorida Keys to Fort Myersby car, plane, or bus

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There are 4 ways to get from Florida Keys to Fort Myers by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive 274.3 mi

    best
    1. Drive from Key West to Fort Myerscar car 274.3 mi
    5h 50m
    $51–73

  2. Fly to Miami International Airport, bus

    1. Fly from Key West International Airport (EYW) to Miami International Airport (MIA)plane plane EYW - MIA
    2. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    5h 24m
    $59–302

  3. Fly to Tampa, bus

    1. Fly from Key West International Airport (EYW) to Tampa (TPA)plane plane EYW - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    6h 22m
    $101–422

  4. Fly to Orlando, bus

    1. Fly from Key West International Airport (EYW) to Orlando (MCO)plane plane EYW - MCO
    2. Take the bus from Orlando to Fort Myers Bus Stopbus bus
    8h 39m
    $107–693

Key West International Airport (EYW) to Miami International Airport (MIA) flights

Calendar27Weekly Planes
Duration58 minAverage Duration
Ticket$35Cheapest Price
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Questions & Answers

Map of how to get from Florida Keys to Fort Myers.ExpandLaunch map view
  • Distance: 274.3 mi
  • Duration: 5h 50m

What companies run services between Florida Keys, Monroe County, FL, USA and Fort Myers, FL, USA?

You can drive from Key West to Fort Myers in around 5h 50m.

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Bus operators

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