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How to get fromFlorida Keys to Columbusby plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

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There are 6 ways to get from Florida Keys to Columbus by plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Key West International Airport

    best
    1. Fly from Key West International Airport (EYW) to John Glenn Columbus International Airport (CMH)plane plane EYW - CMH
    8h 33m
    $234–767

  2. Bus

    cheapest
    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Columbusbus bus
    35h 23m
    $216–434

  3. Bus, train

    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    2. Take the train from Miami Amtrak Station to Pittsburgh Amtrak Stationtrain train
    3. Take the bus from Pittsburgh Intermodal Station to Columbusbus bus
    46h 57m
    $566–1,222

  4. Drive 1,288.2 mi

    1. Drive from Florida Keys to Columbuscar car 1,288.2 mi
    22h 22m
    $236–340

  5. Shuttle to Miami International Airport, fly

    1. Take a shuttle bus from Big Pine Key, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to John Glenn Columbus International Airport (CMH)plane plane MIA - CMH
    9h 28m
    $624–1,287

  6. Shuttle to Fort Lauderdale–Hollywood International Airport, fly

    1. Take a shuttle bus from Big Pine Key, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to John Glenn Columbus International Airport (CMH)plane plane FLL - CMH
    9h 43m
    $504–1,607

Florida Keys to Columbus by foot and bus

Calendar14Weekly Services
Duration35h 23mAverage Duration
Ticket$216Cheapest Price
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Questions & Answers

Map of how to get from Florida Keys to Columbus.ExpandLaunch map view
  • Distance: 1,118.1 mi
  • Duration: 8h 33m

What companies run services between Florida Keys, FL, USA and Columbus, OH, USA?

Delta, United Airlines, and American Airlines fly from Key West International Airport (EYW) to John Glenn Columbus International Airport (CMH) every 3 hours. Alternatively, you can take a vehicle from Florida Keys to Columbus via Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Atlanta Bus Station in around 35h 23m.

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