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How to get fromFlorida Keys to Destinby plane, bus, taxi, car, or shuttle

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There are 8 ways to get from Florida Keys to Destin by plane, bus, taxi, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Key West International Airport to Destin–Fort Walton Beach Airport

    best
    1. Fly from Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS)plane plane EYW - VPS
    7h 55m
    $192–529

  2. Drive  730.5 mi

    cheapest
    1. Drive from Florida Keys to Destincar car 730.5 mi
    14h 26m
    $134–193

  3. Bus, taxi via Sandy Springs

    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Mobilebus bus
    4. Take the bus from Loxley to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    29h 1m
    $320–467

  4. Fly Key West International Airport to Pensacola International Airport, taxi

    1. Fly from Key West International Airport (EYW) to Pensacola International Airport (PNS)plane plane EYW - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    8h 13m
    $262–564

  5. Fly Key West International Airport to Northwest Florida Beaches International Airport, taxi

    1. Fly from Key West International Airport (EYW) to Northwest Florida Beaches International Airport (ECP)plane plane EYW - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    8h 1m
    $307–704

  6. Shuttle to Miami International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take a shuttle bus from Big Pine Key, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Destin–Fort Walton Beach Airport (VPS)plane plane MIA - VPS
    7h 45m
    $247–579

  7. Shuttle to Miami International Airport, fly to Pensacola International Airport, taxi

    1. Take a shuttle bus from Big Pine Key, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Pensacola International Airport (PNS)plane plane MIA - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    8h 38m
    $317–624

  8. Bus, taxi

    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Montgomery Intermodal Centerbus bus
    4. Take the bus from Montgomery Intermodal Center to Biloxi Transit Centerbus bus
    5. Take the bus from Biloxi to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    35h 48m
    $307–464

Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar47Weekly Planes
Duration6h 31mAverage Duration
Ticket$64Cheapest Price
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Comparing Your Travel Options

Map of how to get from Florida Keys to Destin.ExpandLaunch map view
  • Distance: 556.5 mi
  • Duration: 7h 55m

What companies run services between Florida Keys, FL, USA and Destin, FL, USA?

American Airlines, Delta, and Allegiant Air fly from Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS) every 4 hours.

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