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How to get fromFlorida Keys to New Orleansby plane, shuttle, bus, car, train, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Florida Keys to New Orleans by plane, shuttle, bus, car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Key West International Airport to Louis Armstrong New Orleans International Airport

    best
    1. Fly from Key West International Airport (EYW) to Louis Armstrong New Orleans International Airport (MSY)plane plane EYW - MSY
    7h 40m
    $533–967

  2. Drive 986.2 mi

    cheapest
    1. Drive from Florida Keys to New Orleanscar car 986.2 mi
    17h 26m
    $180–260

  3. Shuttle, bus

    1. Take a shuttle bus from Summerland Key - Mote Marine Lab to Miami, FL - International Airportshuttle bus
    2. Take the bus from Miami Airport to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    26h 25m
    $361–566

  4. Shuttle to Miami International Airport, fly to Louis Armstrong New Orleans International Airport

    1. Take a shuttle bus from Big Pine Key, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Louis Armstrong New Orleans International Airport (MSY)plane plane MIA - MSY
    8h 41m
    $653–1,137

  5. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Louis Armstrong New Orleans International Airport

    1. Take a shuttle bus from Big Pine Key, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Louis Armstrong New Orleans International Airport (MSY)plane plane FLL - MSY
    9h 11m
    $463–1,407

  6. Fly Key West International Airport to Gulfport-Biloxi Regional Airport, train

    1. Fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT)plane plane EYW - GPT
    2. Take the train from Gulfport, MS to New Orleans, LA - Union Passenger Terminaltrain train
    11h 38m
    $230–650

  7. Bus

    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    30h 43m
    $209–369

Florida Keys to New Orleans by foot and bus

Calendar19Weekly Services
Duration30h 43mAverage Duration
Ticket$209Cheapest Price
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Questions & Answers

Map of how to get from Florida Keys to New Orleans.ExpandLaunch map view
  • Distance: 690.7 mi
  • Duration: 7h 40m

What companies run services between Florida Keys, FL, USA and New Orleans, LA, USA?

American Airlines, Delta, and Breeze Airways fly from Key West International Airport (EYW) to Louis Armstrong New Orleans International Airport (MSY) every 4 hours. Alternatively, you can take a vehicle from Florida Keys to New Orleans Bus Station via Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Tallahassee, and Mobile Bus Station in around 30h 43m.

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